Knee Injury Clinical Trial
Official title:
Dexamethasone as an Adjuvant to Ropivacaine for Femoral Nerve Blocks in Children Undergoing Knee Arthroscopy
Verified date | November 2018 |
Source | Nationwide Children's Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
If preservative-free dexamethasone 0.1 mg/kg (max dose 4 mg) is added to ropivacaine 0.5% 2 mg/kg (max dose 100 mg), then post-PACU opioid consumption will be reduced by 33%.
Status | Completed |
Enrollment | 77 |
Est. completion date | September 2016 |
Est. primary completion date | July 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 10 Years to 19 Years |
Eligibility |
Inclusion Criteria: - Children older than 10, and younger than 19 years of age undergoing unilateral arthroscopic surgery of the knee - American Society of Anesthesiologists (ASA) Status I or II - Patient's parent/guardian willing and able to give consent - Patient willing to give assent Exclusion Criteria: - Arthroscopic anterior cruciate ligament repair - Systemic steroid use within the last 3 months - Diabetes mellitus - Females testing positive for pregnancy - BMI > 98th percentile - Positive pregnancy test - Coagulopathy - Renal or hepatic disease - Pre-existing motor or sensory deficits in the lower extremities - Predisposition for falls based on pre-existing sensory or motor deficits of the legs or inability to perform crutch training. - Non-English speaking - Systemic fungal infection - Immunosuppressed patients |
Country | Name | City | State |
---|---|---|---|
United States | Nationwide Children's Hospital | Columbus | Ohio |
Lead Sponsor | Collaborator |
---|---|
Nationwide Children's Hospital |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Intra-operative and Post-operative Opioid Consumption | Number of doses of narcotic pain medicine administered during surgery and up to 48 hours after discharge from surgery center. | Intra-operative and up to 48 hours post-discharge, an average of 48 hours | |
Secondary | Post-operative Pain Scores | Visual Analogue Scale (VAS) pain scores (0 being no pain and 10 being worst pain) from arrival to post-anesthesia care unit (PACU) to 48 hours after discharge from surgery center. | Immediately post-operatively and up to 48 hours post-discharge, an average of 48 hours |
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