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Knee Arthroplasty clinical trials

View clinical trials related to Knee Arthroplasty.

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NCT ID: NCT01225484 Recruiting - Knee Arthroplasty Clinical Trials

Perioperative Analgesia After Knee Arthroplasty

Start date: October 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The second method uses periarticular infiltration of ropivacaine in combination with an bolus of ropivacaine into an intraarticular catheter placed intraoperatively followed by a continuous intraarticular infusion of ropivacaine. All patient will also receive a sustained-release oral opioid and oral rescue opioids determined by pain severity using the Visual Analog Scale (VAS)

NCT ID: NCT01191593 Completed - Postoperative Pain Clinical Trials

The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Revision Knee Arthroplasty

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether Adductor-Canal-Blockade is effective at reducing pain and morphine consumption after revision knee arthroplasty.

NCT ID: NCT01140815 Completed - Knee Arthroplasty Clinical Trials

Functional Performance of the Journey Deuce Bicompartmental Versus the Genesis II Total Knee System

Deuce
Start date: September 2007
Phase: Phase 4
Study type: Interventional

The objectives of this study are to assess the safety and effectiveness of the Journey Deuce Bicompartmental Knee System at 4-6 weeks, 4 months, 1 year, and 2 years when compared to total knee replacement using the Genesis II Total Knee System. The hypothesis is that the Journey Deuce Bicompartmental Knee System is as safe and effective as the Genesis II Total Knee System at the 2-year. The null hypothesis is that there is no difference between the groups.

NCT ID: NCT01003080 Completed - Knee Arthroplasty Clinical Trials

Unipolar vs. Bipolar Hemostasis in Total Knee Arthroplasty: A Prospective Randomized Trial

Start date: August 2009
Phase: N/A
Study type: Interventional

The use of Aquamantys during total knee arthroplasty will reduce drain output and the necessity for blood transfusions.

NCT ID: NCT00803348 Completed - Knee Arthroplasty Clinical Trials

Continuous Femoral Nerve Blockade and Readiness to Discharge Following Total Knee Arthroplasty

Start date: May 2009
Phase: N/A
Study type: Interventional

Patients undergoing total knee arthroscopy (knee replacement) surgery usually receive a femoral nerve block as part of their anesthetic care. Some centers administer the block with a single shot of local anesthetic, which wears off several hours after surgery. Other centers administer the block with a single shot followed by continuous infusion of local anesthetic, typically for 2 to 5 days after surgery. The latter method, though good for pain control, may result in decreased mobility (while the anesthetic is still active), longer hospital stays, and greater risk of falls. This study will see if using a lower concentration of local anesthetic for the continuous femoral nerve block or only the initial single-shot dose will result in increased mobility and shorter hospital stays.

NCT ID: NCT00759616 Completed - Knee Arthroplasty Clinical Trials

Outcome Analysis of the Oxford Partial Knee Arthroplasty

Start date: April 2003
Phase: N/A
Study type: Interventional

Prospectively monitor the patients receiving the Oxford Partial knee arthroplasty

NCT ID: NCT00679614 Completed - Spinal Anesthesia Clinical Trials

Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery

Start date: December 17, 2007
Phase: Phase 3
Study type: Interventional

Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period. The primary objective is to determine opioid use during combined use of oral tramacet and naloxone infusion perioperatively in elderly patients (70 yrs and older) having elective knee/ hip arthroplasty under spinal anesthesia. Secondary objectives are to determine the incidence VAS scores ≥4 and adverse effects such as nausea, vomiting, sedation, respiratory depression, pruritus, confusion, and time of independent mobilization. Hypothesis: Perioperative naloxone infusion and tramacet provides adequate analgesia in elderly patients undergoing total knee/hip arthroplasty and is associated with 80% reduction in opioid use and reduced opioid-induced side effects.

NCT ID: NCT00616044 Not yet recruiting - Hip Fractures Clinical Trials

Continuous Spinal Anesthesia Versus Combined Spinal Epidural Block

Spinocath
Start date: March 2008
Phase: N/A
Study type: Interventional

In major orthopaedic surgery of the lower extremities both continuous spinal anesthesia (CSA) and combined spinal epidural anesthesia (CSE) are safe and reliable anaesthesia methods. Our results suggest that both continuous spinal anesthesia and combined spinal epidural anesthesia provide good surgical conditions with a low incidence of complications. The sensory block level and hemodynamic changes were lesser with CSA.

NCT ID: NCT00454467 Active, not recruiting - Knee Arthroplasty Clinical Trials

Hospital for Special Surgery Knee Arthroplasty Cohort

Start date: April 2007
Phase:
Study type: Observational

Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk. In 2002, over 200,000 total hip replacements, 350,000 total knee replacements, and 25,000 total or partial shoulder replacements were performed in the United States (HCUP data). Future use will likely be even higher: it is estimated that by the year 2020, the population 65 and over in developed countries will increase by 71%. Existing studies do not provide adequate prospective data to evaluate long-term outcomes. Most health related quality of life studies in THA and TKA only report data up to twelve months post-operatively. In addition, most large studies of TKA and THA have been performed in Medicare patients. While these databases are important in providing population based data, Medicare studies do not permit any direct patient contact, and provide no information on patients under 65. Existing studies have also investigated predictors of patient outcome at one and two years after joint arthroplasty. However, very little is known about predictors of prosthesis failure, and there are no validated clinical indicators for choosing one prosthesis model over another. Once a device is FDA approved, there is very little motivation on the part of the developer to perform complete post-marketing research, despite the importance of these data to the public health. Most existent studies are not powered to compare differences between models. The purpose of this study is to establish a prospective cohort of HSS total knee arthroplasty.

NCT ID: NCT00367289 Completed - Knee Arthroplasty Clinical Trials

CT for Diagnosis of Implant Stability in Revision Arthroplasty

Start date: October 2007
Phase: N/A
Study type: Observational

All patients over 18 who undergo a revision of hip or knee arthroplasty will be included. Patients undergo a CT of the hip joint. A radiologist will mark the presence of cysts and bone loss and will assess implant stability. After the surgery, the surgeon will fill a similar form.