Knee Arthritis Clinical Trial
Official title:
QIST Collaborative - Arthroplasty Research Cohort (ARC) Study - A Collaborative, Longitudinal Observational Cohort Study of Patients Undergoing Primary Hip and Knee Replacements in the United Kingdom
The ARC Study is a national observational cohort study to investigate patient reported and clinical outcomes after hip and knee replacements. The study has the following objectives: 1. To evaluate outcomes following hip and knee replacements. 2. To determine risk factors for adverse outcomes in primary hip and knee replacements. 3. To identify targets for future research and intervention in patients undergoing primary hip and knee replacements 4. To provide a resource from which to identify potential participants for future clinical trials, and to use data collected in the ARC Study as comparison or control data for trial participants who have been randomised to receive one or more interventions. Participants are recruited and consented online. Patients are invited to participate by collaborating surgical teams nationally in outpatient clinics at the time of being added to a waiting list, in addition to an advertising campaign to recruit patients. They are directed to an online portal where they will be able to review further information. Consent and data collection is completed electronically through patients entering data online. Baseline demographics and characteristics are recorded, including details of socio-demographics, lifestyle, health status and patient reported outcome measures (PROMs). Patients then undergo hip/knee replacement and postoperative rehabilitation according to the standard care and protocols of the hospital and the preferences of their treating surgeon. Follow-up data, including PROMs, is collected via online questionnaires up to two years following surgery. The study will ultimately also enable multiple trials to be embedded within the cohort study, using a 'Trials within Cohorts' (TwiCs) methodology.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05464862 -
The Effect of PPB Using 10, 20 and 30 ml of Lidocaine, Study on Volunteers
|
Phase 4 | |
| Completed |
NCT05346822 -
The Efficacy of Collaborative Patient Education on Total Knee Arthroplasty
|
N/A | |
| Completed |
NCT05420194 -
Assessment of Postural Stability in Patients With Total Knee Arthroplasty
|
||
| Active, not recruiting |
NCT03211663 -
Performance of MOTO Medial® Unicompartmental Knee Arthroplasty
|
||
| Recruiting |
NCT04952220 -
Exploratory Study of Ultrasound Signs of Native Septic Arthritis of the Knee
|
||
| Completed |
NCT01560767 -
Perioperative Analgesia for Knee Arthroplasty (PAKA)
|
Phase 4 | |
| Recruiting |
NCT05566561 -
Para-sartorial Compartment Block in Knee Surgery
|
N/A | |
| Recruiting |
NCT05859269 -
Methylprednisolone Taper, Lower Extremity
|
Phase 4 | |
| Completed |
NCT03071250 -
An Analysis of the Outcomes From Protocolized Perioperative Care for Patients Receiving Total Hip or Knee Arthroplasty
|
||
| Completed |
NCT03302832 -
Effectiveness of Reduced Frequency Physical Therapy in Total Knee Arthroplasty
|
N/A | |
| Active, not recruiting |
NCT04620525 -
Cognition, Pain and Wellbeing
|
||
| Completed |
NCT05621161 -
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
|
N/A | |
| Completed |
NCT01242085 -
Preoperative Alignment of Total Knee Replacement
|
Phase 3 | |
| Withdrawn |
NCT00589485 -
Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement
|
N/A | |
| Recruiting |
NCT04163445 -
Comparison of TKAs Using Force Plate Analysis
|
N/A | |
| Completed |
NCT05975879 -
A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis
|
N/A | |
| Not yet recruiting |
NCT06284824 -
Comparison of Two Robotic-Assisted Total Knee Arthroplasty Systems
|
N/A | |
| Completed |
NCT01124305 -
Knee Arthroplasty Performed With Conventional and Customized Instrumentation
|
Phase 4 | |
| Completed |
NCT00862316 -
Oxford Unicompartmental Knee Arthroplasty With and Without Navigational Unit
|
N/A | |
| Completed |
NCT04496856 -
Effects of Whey and Collagen on FFM, Muscle Strength and Wound Healing in Elderly Surgical Patients
|
N/A |