Kidney Transplant Recipients Clinical Trial
Official title:
A Randomized, Open-label, Multi-center Clinical Trial to Compare Efficacy and Safety of Cyclosporine-based and Switching Cyclosporine to Tacrolimus of Two Forms-based Immunosuppressive Therapy in Renal Transplant (KTx) Recipients
KTx recipients receiving cyclosporine-based immunosuppressive therapy, and in the opinion of the investigator would benefit from switch to a tacrolimus-based immunosuppression, will switch the immunosuppressive therapy to a tacrolimus-based one. Efficacy and safety of patients will be observed for 52 weeks.
The primary objective of this study is to compare the adherence of kidney transplant
recipients treated with Prograf and Advagraf regimens.
The secondary objectives of this study are:
- To compare the renal function (eGFR) in KTx recipients treated with Cyclosporine and
Tacrolimus regimens.
- To compare the QoL of KTx recipients treated with Cyclosporine and Tacrolimus regimens.
- To compare the efficacy of Cyclosporine and Tacrolimus regimens in KTx recipients.
- To compare the safety of Cyclosporine and Tacrolimus regimens in KTx recipients.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01336296 -
Evaluate Effects and Safety of Pre-load Myfortic® in Transplant Patients
|
Phase 4 | |
| Recruiting |
NCT01150487 -
Paired Marrow Aspirations to Assess Assays in Sensitized Renal Allograft Recipients
|
N/A | |
| Recruiting |
NCT05938712 -
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
|
Phase 2 | |
| Completed |
NCT00217100 -
A Multivitamin Comparison Study in Kidney Transplant Recipients.
|
Phase 3 | |
| Active, not recruiting |
NCT00199667 -
Concentration Controlled Versus Fixed Dose of MMF in Kidney Transplant Recipients
|
Phase 4 | |
| Terminated |
NCT01517984 -
Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation
|
Phase 2 | |
| Recruiting |
NCT04642833 -
Prostate Cancer in Renal Transplants Recipients
|
||
| Not yet recruiting |
NCT05293704 -
An Open Study on the Preventive Effect of Early Mizoribine Conversion on BKV Nephropathy in Renal Transplant Recipients
|
Phase 4 | |
| Completed |
NCT02555566 -
Role of Epoxyeicosatrienoic Acids in Chronic Allograft Nephropathy - The TRANSPLANT-EETs Study
|
N/A | |
| Completed |
NCT01782586 -
Validation of Gene Expression Markers of Renal Allograft Functional Decline
|
||
| Enrolling by invitation |
NCT02042963 -
KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation (KNOW-KT)
|
N/A | |
| Not yet recruiting |
NCT05702398 -
Pilot Trial of Supplemental Vitamin A and Nicotinamide
|
Early Phase 1 | |
| Active, not recruiting |
NCT05425498 -
The Effects of Physical Activity Behavior Change in Kidney Transplant Recipients
|
N/A | |
| Completed |
NCT01889758 -
Pharmacokinetic Studies of Tacrolimus in Transplant Patients
|
Phase 4 | |
| Active, not recruiting |
NCT03979365 -
Envarsus XR Compared to Immediate Release Tacrolimus
|
Phase 4 | |
| Recruiting |
NCT04965935 -
Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients
|
Phase 3 | |
| Recruiting |
NCT04444843 -
Risk Factors of Chinese Kidney Transplant Recipients DSA Based on MPA Immunosuppressive Regimen
|
Phase 4 | |
| Completed |
NCT02392312 -
Observational Study to Evaluate the Safety and Efficacy of ATG-F on Kidney Transplant Recipients
|
||
| Completed |
NCT02639949 -
Measuring and Improving Medication Adherence in Kidney Transplant Patients
|
N/A | |
| Withdrawn |
NCT02058875 -
Cardiovascular Risk Following Conversion to Full Dose Myfortic® and Neoral® Two-hour Post Level Monitoring
|
Phase 4 |