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Kidney Transplantation clinical trials

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NCT ID: NCT06320821 Enrolling by invitation - Clinical trials for Kidney Transplantation

RAKT OUTCOME ANALYSIS

Start date: August 21, 2021
Phase:
Study type: Observational

The goal of this observational study is to compare outcomes of robot-assisted kidney transplantation and open kidney transplantation. The main questions are - comprehensively analyze our early experience of robot-assisted kidney transplant patients and compare the results with those of open kidney transplant patients

NCT ID: NCT06126380 Enrolling by invitation - Clinical trials for Kidney Transplant Rejection

Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients

Start date: October 25, 2023
Phase: Phase 2
Study type: Interventional

This study will evaluate the long term safety and efficacy of AT-1501 (tegoprubart) compared with tacrolimus in patients undergoing kidney transplantation.

NCT ID: NCT05987527 Enrolling by invitation - Clinical trials for End Stage Renal Disease

Long-Term Follow-Up of TX200-TR101 (STEADFAST Long Term)

Start date: August 15, 2023
Phase:
Study type: Observational

This long-term follow-up study is being conducted to collect long-term (up to 15 years post-infusion) safety and tolerability data from subjects enrolled in studies evaluating TX200-TR101.

NCT ID: NCT05948059 Enrolling by invitation - Clinical trials for Kidney Transplantation

Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects

Start date: July 11, 2023
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, placebo-controlled phase I clinical study with the primary objective of evaluating the safety and tolerability of SHR-2106 in healthy subjects after a single intravenous or subcutaneous administration.

NCT ID: NCT05797337 Enrolling by invitation - Kidney Transplant Clinical Trials

Knowledge and Attitude of Dialysis Center Medical Staff Towards Living Kidney Donation

Start date: February 28, 2023
Phase:
Study type: Observational

The goal of this cross-sectional study is to learn about the level of knowledge and attitudes of medical staff working in dialysis centers about living kidney donations. The main questions it aims to answer are: - What is the level of knowledge of dialysis center medical staff regarding living kidney transplantations? - How much time does the staff have for educating the patients about living kidney donations? Participants will be asked to answer a self-report questionnaire along with two standardized tools.

NCT ID: NCT05285878 Enrolling by invitation - Clinical trials for Kidney Failure, Chronic

Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

Start date: July 28, 2022
Phase: Phase 2
Study type: Interventional

This is a randomized, double-blind, placebo-controlled trial in de novo kidney transplant patients to determine if the addition of fingolimod (brand name Gilenya®, candidate name- FTY720) on the background of standard immunosuppression will prevent expansion of the interstitial compartment of the transplanted kidney. Interstitial expansion is the precursor of interstitial fibrosis and graft loss. The study will test the hypothesis that abgrogating the fibrogenic effects of both the RhoA and mTOR pathways with fingolimod will reduce structural damage in transplanted kidneys and possible subsequent transplant failure.

NCT ID: NCT05224583 Enrolling by invitation - Clinical trials for Kidney Transplant Infection

Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant

Start date: November 17, 2021
Phase:
Study type: Observational

The human BK polyomavirus is a significant risk factor for renal transplant dysfunction and allograft loss. The prevalence of BK viremia (BKV) following kidney transplantation is estimated to be 10-20%.

NCT ID: NCT04398498 Enrolling by invitation - Clinical trials for Kidney Transplant Rejection

Molecular Biomarkers in Renal Transplantation Via TruGraf® Test

Start date: April 13, 2020
Phase:
Study type: Observational

The TruGraf® test is a non-invasive blood test that measures molecular gene expression profiles associated with clinical conditions previously only diagnosed by biopsy in kidney transplant recipients. The results of the TruGraf test provide additional information about the adequacy of immunosuppression and may be used to support decisions in patient management.

NCT ID: NCT04363515 Enrolling by invitation - Kidney Transplant Clinical Trials

Pilot Social Support Counseling Intervention for Kidney Transplant Candidates

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Pilot social support counseling intervention for kidney transplant candidates

NCT ID: NCT04281797 Enrolling by invitation - Clinical trials for Microbial Colonization

Intestinal Microbiome Dynamics in Solid Organ and Stem Cell Transplant Recipients

Start date: January 1, 2020
Phase:
Study type: Observational

This is a pilot study designed to investigate the alterations in the gut microbiome that occur during the course of kidney transplantation, liver transplantation, allogeneic hematopoietic stem cells and mesenchymal stem cells transplantation in association with the clinical outcomes.