How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis

Status Completed

Clinical Trial Summary

Patients with chronic kidney disease and end stage renal disease have greater cardiovascular risk than the general population. Vitamin D analogues have been shown in observational studies to have mortality benefit for these patients. This study is designed to investigate doxercalciferol's effect on the vasculature (i.e. endothelial cell function) as a possible mechanism to explain the mortality benefit.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00528788
Study type	Interventional
Source	Duke University
Contact
Status	Completed
Phase	Phase 4
Start date	September 2007
Completion date	August 2012

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