Kidney Cancer Clinical Trial
Official title:
Phase II Trial of Bevacizumab(Avastin) and RAD001(Everolimus)in the Treatment of Patients With Advanced Clear Cell Renal Carcinoma
This phase II trial will evaluate the combination of bevacizumab + RAD001 in patients with metastatic renal cell carcinoma. In this trial the investigators will evaluate this combination in patients previously untreated with any anti-angiogenesis agent and patients who have previously received one prior regimen containing an anti-angiogenesis agent.
All eligible patients will receive:
- Bevacizumab 10mg/kg, IV infusion, every 2 weeks
- RAD001 10 mg by mouth daily
All patients will be evaluated for response after completing two courses (8 weeks) of
treatment. Patients with objective tumor response or stable disease will continue treatment
with bevacizumab adn RAD001 on the same schedule. Treatment will continue until disease
progression occurs.
;
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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