Kidney Cancer Clinical Trial
Official title:
A Phase 2 Study Of UCN-01 In Advanced Renal Cell Carcinoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing
so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of UCN-01 in treating patients who have
unresectable stage III or stage IV kidney cancer.
OBJECTIVES:
- Determine the efficacy of UCN-01, in terms of time to objective progression, in
patients with stage IV or unresectable stage III renal cell carcinoma.
- Determine the objective response rate in patients treated with this drug.
OUTLINE: Patients receive UCN-01 IV over 3 hours on day 1. Courses repeat every 3 weeks in
the absence of disease progression or unacceptable toxicity.
PROJECTED ACCRUAL: A total of 21-61 patients will be accrued for this study within 15
months.
;
Primary Purpose: Treatment
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