Kidney Cancer Clinical Trial
Official title:
A Trial of ZD1839 (Iressa) in Patients With Advanced Renal Cell Carcinoma
RATIONALE: Some tumors need growth factors produced by the body's white blood cells to keep
growing. Drugs such as ZD 1839 may interfere with the growth factors and cause tumor cells
to die.
PURPOSE: Phase II trial to study the effectiveness of ZD 1839 in treating patients who have
metastatic kidney cancer.
OBJECTIVES: I. Determine the efficacy of ZD 1839 in patients with metastatic renal cell
cancer. II. Determine the time to disease progression in patients treated with this drug.
III. Determine the safety of this drug in these patients.
OUTLINE: Patients receive oral ZD 1839 once daily. Courses repeat every 28 days in the
absence of disease progression or unacceptable toxicity. Patients are followed for at least
1 month.
PROJECTED ACCRUAL: A total of 16-46 patients will be accrued for this study within 1 year.
;
Primary Purpose: Treatment
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