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Keratosis clinical trials

View clinical trials related to Keratosis.

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NCT ID: NCT03315286 Completed - Skin Cancer Clinical Trials

Validation of SHADE a Mobile Technology for Monitoring of Ultraviolet Exposure

Start date: October 11, 2017
Phase: N/A
Study type: Interventional

This study will evaluate the safety and effectiveness of Shade for the management of UV-induced skin complications and data collected from this study will be used to support the proposed indications for use.

NCT ID: NCT03285490 Completed - Actinic Keratosis Clinical Trials

A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on Actinic Keratosis on Face or Scalp (AK004)

Start date: September 15, 2017
Phase: Phase 3
Study type: Interventional

This Phase III study was designed to evaluate the efficacy and safety of KX2-391 Ointment 1% in adult participants when applied to an area of skin containing 4-8 stable, clinically typical actinic keratosis (AK) lesions on the face or scalp.

NCT ID: NCT03285477 Completed - Actinic Keratoses Clinical Trials

A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp

AK003
Start date: September 18, 2017
Phase: Phase 3
Study type: Interventional

This Phase III study is designed to evaluate the efficacy and safety of KX2-391 Ointment in adult participants when applied to an area of skin containing 4-8 stable, clinically typical Actinic Keratosis (AK) lesions on the face or scalp.

NCT ID: NCT03279328 Completed - Actinic Keratoses Clinical Trials

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents

Start date: October 10, 2017
Phase: Phase 4
Study type: Interventional

This proposed project will be an open-label, split face, randomized controlled pilot study. Up to 60 patients with diffuse facial actinic keratosis will be enrolled in the study. The purpose of this study is to understand the change in skin appearance throughout 5-FU treatment course and to examine whether a topical corticosteroid and moisturizer can decrease severity and duration of skin inflammation after 5-FU treatment course.

NCT ID: NCT03246412 Completed - Melanoma (Skin) Clinical Trials

Nevus Doctor Clinical Decision Support for GPs

Start date: January 17, 2018
Phase: N/A
Study type: Interventional

The study investigates if a computer-based clinical decision support tool for skin cancer may improve the diagnostic accuracy of general practitioners (GPs). The aim of the program is to help GPs increase their diagnostic accuracy, in particular regarding the selection of suspicious skin lesions that need biopsy or referral to specialist health care for further assessment. Half of the physicians in the trial will have the clinical decision support tool available during consultations, while the other half has no such tool available. We hypothesize that general practitioners using the clinical decision support tool will have a higher number of correct classifications of skin lesions compared to doctors without the tool.

NCT ID: NCT03243617 Completed - Keratosis Pilaris Clinical Trials

Cosmetic Study of AO+Mist in Improving the Appearance of Skin Afflicted With Keratosis Pilaris

Start date: December 4, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to demonstrate the safety, tolerability and efficacy of AO+ Mist administered daily for 4 weeks to improve the appearance of skin afflicted with keratosis pilaris.

NCT ID: NCT03210740 Completed - Actinic Keratosis Clinical Trials

Safety and Efficacy Study of AM001 Cream in the Treatment of Actinic Keratosis

Start date: June 6, 2017
Phase: Phase 2
Study type: Interventional

To compare the safety and efficacy profiles of AM001 Cream, 7.5% and its vehicle cream in the treatment of Actinic Keratosis (AK) Lesions

NCT ID: NCT03200912 Completed - ACTINIC KERATOSIS Clinical Trials

An Equivalence Study of Generic Ingenol Mebutate Gel 0.015% and Picato Gel 0.015% in Subjects With Actinic Keratosis

Start date: August 19, 2016
Phase: Phase 3
Study type: Interventional

The objective of this study was to evaluate the safety and therapeutic equivalence of generic ingenol mebutate gel, 0.015% to Picato gel, 0.015% by establishing the therapeutic comparability of the two active products and the superiority of the two active products over the vehicle gel in the treatment of AK on the face and scalp.

NCT ID: NCT03148691 Completed - Clinical trials for Seborrheic Keratosis

A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Treatment of Seborrheic Keratosis

Start date: May 17, 2017
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the safety and effectiveness of 2 concentrations of A-101 compared to Vehicle for the treatment of 4 seborrheic keratosis (SK) Target Lesions on the trunk, extremities and face.

NCT ID: NCT03127670 Completed - Arsenical Keratosis Clinical Trials

Effect of Solanum Melongena Extract in the Treatment of Arsenical Skin Lesion

Start date: November 14, 2016
Phase: Phase 2
Study type: Interventional

Solanum melongena is a common vegetable contains phytochemicals which prevent, reduce or delay the oxidation of DNA and alter the cellular signal transduction pathways controlling cell proliferation and apoptosis of human cancer. The skin of Solanum melongena peel contains nasunin an anthocyanins and chlorogenic acid which have anti-inflammatory, antioxidant, antimutagenic and antiangiogenic properties. Extract of Solanum melongena is used in actinic keratosis and Squamous cell carcinoma of the skin. This study will determine any change in arsenical skin lesion after administrating Solanum melongena extract cream.