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Keratosis clinical trials

View clinical trials related to Keratosis.

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NCT ID: NCT01532453 Terminated - Actinic Keratoses Clinical Trials

Prevention of UV-induced Carcinogenic Skin Alterations in Immunosuppressed Solid Organ Transplanted Patients

Start date: November 2010
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to investigate the prevention of actinic keratoses and squamous cell carcinomas by local application of MD-3511356 in comparison to standard sun protection measures in immunosuppressed solid organ transplant recipients.

NCT ID: NCT01525329 Terminated - Actinic Keratosis Clinical Trials

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

Start date: September 2011
Phase: Phase 3
Study type: Interventional

This randomized, intra-patient comparative study is designed to investigate the combination regimen of 5-fluorouracil cream (5FU) and Photodynamic Therapy (PDT), versus PDT alone, for its ability to generate significantly elevated levels of the target photosensitizer, protoporphyrin IX (PpIX), in lesions of actinic keratoses (AKs) and to more effectively treat and prevent recurrence of AKs. The target population comprises patients with solid organ transplants (renal, hepatic), as well as normal (immunocompetent) subjects to control for possible influences of immunosuppression.

NCT ID: NCT01203878 Terminated - Actinic Keratosis Clinical Trials

Treatment of Actinic Keratoses of the Face With Imiquimod 3.75% Cream Followed by Photodynamic Therapy

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to explore the effect of treating actinic keratoses of the face with imiquimod 3.75% cream followed by photodynamic therapy in comparison to treatment with imiquimod alone

NCT ID: NCT00944216 Terminated - Keratosis Pilaris Clinical Trials

Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study

Start date: June 2009
Phase: Phase 4
Study type: Interventional

Keratosis pilaris (KP) is a benign skin condition that often is very frustrating for the patients and treating physicians. The investigators are interested to see if the study product is effective in treating moderate to severe KP.

NCT ID: NCT00865878 Terminated - Actinic Keratoses Clinical Trials

ALA-PDT Versus Vehicle PDT for Treatment of AK and Reduction of New NMSC in Solid Organ Transplant Recipients

Start date: May 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine and compare the safety and efficacy of broad area photodynamic therapy with aminolevulinic acid (ALA-PDT) versus vehicle PDT (VEH-PDT) in the treatment of actinic keratoses (AK) and reduction of new non-melanoma skin cancer (NMSC) of the scalp or both forearms in solid organ transplant recipient subjects receiving chronic immunosuppressive therapy.

NCT ID: NCT00524485 Terminated - Clinical trials for Precancerous/Nonmalignant Condition

Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis

Start date: May 2005
Phase: N/A
Study type: Interventional

RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, abnormal cells are killed. Photodynamic therapy using topical aminolevulinic acid may be effective against actinic keratosis. PURPOSE: This randomized clinical trial is studying how well different photodynamic therapy regimens using topical aminolevulinic acid work in treating patients with actinic keratosis.

NCT ID: NCT00005097 Terminated - Clinical trials for Non-melanomatous Skin Cancer

Green Tea Extract in Treating Patients With Actinic Keratosis

Start date: August 1999
Phase: Phase 2
Study type: Interventional

RATIONALE: Green tea extract contains ingredients that may inhibit the growth of actinic keratosis. PURPOSE: Randomized phase II trial to determine the effectiveness of green tea extract in treating patients who have actinic keratosis.