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Keratosis clinical trials

View clinical trials related to Keratosis.

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NCT ID: NCT01787383 Completed - Actinic Keratosis Clinical Trials

A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen With Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas With Actinic Keratosis on Face/Scalp and Trunk/Extremities

Start date: February 2013
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to evaluate the safety of a simultaneous treatment regimen compared to a sequential treatment regimen when two separate areas with AKs (one located on face/scalp and the other located on trunk/ extremities) are treated with ingenol mebutate gel

NCT ID: NCT01757613 Completed - Clinical trials for Actinic Keratosis Olsen Grade I/II

Study Whose Purpose is to Find an Optimal Dose for the Treatment With AK 3012 in Patients With Actinic Keratosis

Start date: December 2012
Phase: Phase 2
Study type: Interventional

In this three-armed dose-finding trial 3 AK 3012 topical formulations shall be investigated with respect to safety and efficacy in order to identify the optimal concentration in the topical formulation. The main objective of the trial is to determine the optimal concentration of the active agent in the topical formulation as quantified by the change of the number of skin alterations in pre-defined areas in a time period from inclusion in the trial until the end of treatment (3 months) or prior complete healing.

NCT ID: NCT01752972 Completed - Arsenical Keratosis Clinical Trials

Effect of Spirulina on Zinc, Vitamin E and Linoleic Acid Levels in Palm Skin Following Chronic Exposure to Arsenic

Start date: April 2011
Phase: N/A
Study type: Interventional

Patients of arsenical keratosis may be treated with spirulina. Is this improvement related to the levels of zinc, vitamin E and linoleic acid at the site of the keratosis (palm)? To understand this, patients of palmer arsenical keratosis (n=10), arsenic exposed controls (n=10) and healthy volunteers (n=10) will be treated with spirulina powder 10 g/day orally for 12 weeks. Skin extracts will be collected both before and after supplementation from the palm and dorsum for estimation of zinc, vitamin E and linoleic acid levels.

NCT ID: NCT01748669 Completed - Clinical trials for Chronic Arsenic Poisoning

Effectiveness of Garlic Oil in the Treatment of Arsenical Palmer Keratosis

Start date: October 2011
Phase: Phase 2
Study type: Interventional

Twenty patients of mild to moderate degree of arsenical palmer keratosis will be treated with garlic oil capsule orally for 12 weeks to examine its effectiveness in reducing body arsenic load and clinical symptoms. Similar treatment with similar number of arsenic exposed controls and healthy volunteers will be included for comparison.

NCT ID: NCT01742663 Completed - Actinic Keratosis Clinical Trials

A Study Comparing Diclofenac Sodium Gel 3% to Solaraze® Gel 3% in the Treatment of Actinic Keratosis

Start date: October 2012
Phase: Phase 1
Study type: Interventional

The objective of this study is to compare the relative efficacy and safety of the test formulation diclofenac sodium gel 3% (Taro Pharmaceuticals Inc.) to the marketed formulation Solaraze® (diclofenac sodium) Gel 3% (Fougera Pharms) in the treatment of actinic keratosis. Both the test and reference formulations will also be compared to a placebo formulation to test for superiority.

NCT ID: NCT01735097 Completed - Arsenical Keratosis Clinical Trials

Effect of Nigella Sativa in the Treatment of Palmer Arsenical Keratosis

Start date: January 2013
Phase: N/A
Study type: Interventional

Daily intake of Nigella sativa for 12 weeks is effective in the treatment of palmer arsenical keratosis

NCT ID: NCT01731756 Completed - Arsenical Keratosis Clinical Trials

Effects of Leaf Extract of Azadirachta Indica in Palmer Arsenical Keratosis

Start date: January 2013
Phase: N/A
Study type: Interventional

Effects of leaf extract of Azadirachta indica in palmer arsenical keratosis: Randomized, double-blind, placebo-control trial

NCT ID: NCT01703078 Completed - Actinic Keratosis Clinical Trials

Safety and Tolerability of Different Concentrations of an Ingenol Derivative Field Therapy in the Treatment of Actinic Keratosis

Start date: November 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine if the new ingenol derivative gels are as safe as and as well tolerated as ingenol mebutate gel when applied to AK lesions on the forearm for two consecutive days.

NCT ID: NCT01686152 Completed - Actinic Keratosis Clinical Trials

Study Comparing Imiquimod Cream, 3.75% to Zyclara® (Imiquimod) Cream, 3.75% in the Treatment of Actinic Keratosis

Start date: September 2012
Phase: Phase 3
Study type: Interventional

To determine the comparability of the safety and efficacy of Imiquimod Cream, 3.75% and Zyclara (imiquimod) Cream, 3.75% (the reference listed drug) in subjects with actinic keratosis (AK) of the face or balding scalp. It will also be determined whether the efficacy of each of the two active treatments is superior to that of the Vehicle cream.

NCT ID: NCT01611480 Completed - Actinic Keratosis Clinical Trials

Efficacy and Safety of a New Topical Formulation With Imiquimod (Limtop) Applied 1, 3 or 7 Times Weekly During 2 x 2 Weeks Treatment for Actinic Keratosis on the Head

Start date: n/a
Phase: Phase 2
Study type: Interventional

The aim is to evaluate efficacy and safety of three different dosing regimens of Limtop in a study involving 96 patients with actinic keratosis on the head or face.