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Keratosis clinical trials

View clinical trials related to Keratosis.

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NCT ID: NCT02137785 Completed - Actinic Keratosis Clinical Trials

Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities

Start date: May 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if Levulan Photodynamic Therapy (PDT) is safe and effective in the treatment of actinic keratoses on the upper arms and hands

NCT ID: NCT02126670 Completed - Actinic Keratosis Clinical Trials

ACT01 in Combination With Comp01-04 in Patients With Actinic Keratosis

Start date: April 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether or not ACT01 is effective and tolerable alone or when used in combination with Comp01, Comp02, Comp03 or Comp04 in patients with facial and/or scalp keratosis.

NCT ID: NCT02124733 Completed - Actinic Keratosis Clinical Trials

Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses

Start date: April 2014
Phase: Phase 3
Study type: Interventional

This study is being done to compare a new, continuous illumination regimen of ALA-PDT (Aminolevulinate-Photodynamic Therapy) to a conventional regimen for treatment of actinic keratoses. The hypothesis is that the continuous illumination approach will be less painful, but equally efficacious, as the old regimen.

NCT ID: NCT02124239 Completed - Actinic Keratosis Clinical Trials

Pharmacokinetics of Ingenol Mebutate Gel in Actinic Keratosis Under Maximum Use Conditions

Start date: April 2014
Phase: Phase 1
Study type: Interventional

This is an open-label, uncontrolled, non-randomised multi-centre trial in which 3 parallel groups will be enrolled. The trial includes three active treatment groups. To be eligible for inclusion in this trial, subjects must have at least 10 clinically typical, visible, and discrete AKs on the face, balding scalp or on the arm within a contiguous area of approximately 250 cm2 of sun-damaged skin. There will be 3 treatment groups: (1) once daily application of ingenol mebutate gel 0.027% on the full face for three consecutive days, (2) the same regimen on the balding scalp, and (3) once daily application of ingenol mebutate gel 0.06% on the arm on a treatment area of approximately 250 cm2 for four consecutive days.

NCT ID: NCT02120898 Completed - Actinic Keratosis Clinical Trials

A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses

Start date: October 10, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study it so compare the safety and efficacy profiles of a generic imiquimod 2.5% cream to the reference listed Zyclara® (imiquimod) cream in the treatment of actinic keratosis (AK).

NCT ID: NCT02120456 Completed - Actinic Keratosis Clinical Trials

Safety and Efficacy of Escalating Doses of LEO 43204 Applied Once Daily for Two Consecutive Days on Approximately 250 cm2 on Trunk and Extremities in Subjects With Actinic Keratosis

Start date: May 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Part 1: To identify Maximum Tolerated Dose (MTD) levels of LEO 43204 after once daily treatment for two consecutive days Part 2: To evaluate the efficacy of LEO 43204 in two doses after once daily treatment for two consecutive days compared to vehicle

NCT ID: NCT02100813 Completed - Actinic Keratosis Clinical Trials

Safety and Efficacy of Doses of LEO 43204 Once Daily for Two Consecutive Days on Full Balding Scalp in Subjects With Actinic Keratosis

Start date: May 2014
Phase: Phase 1/Phase 2
Study type: Interventional

To identify the Maximum Tolerated Dose levels of LEO 43204 after once daily treatment for two consecutive days and to evaluate efficacy of LEO 43204 in two doses after once daily treatment for two consecutive days compared to vehicle

NCT ID: NCT02090465 Completed - Actinic Keratosis Clinical Trials

Assessment of Treatment Success and Quality of Life in Patients With Actinic Keratoses Under Therapy With Ingenol Mebutate in a Period of 8 Weeks

Start date: July 2013
Phase:
Study type: Observational

Assessment of treatment success and quality of life in patients with actinic keratoses under therapy with Ingenol Mebutate (Picato) in a period of 8 weeks.

NCT ID: NCT02085395 Completed - Actinic Keratosis Clinical Trials

Clinical Study Assessment of SR-T100 Topical Gel Against Actinic Keratosis

AK
Start date: November 2007
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy of SR-T100 gel by observing the lesion size (length x width x height) of human cutaneous squamous cell carcinoma in situ (Actinic Keratosis and Bowen's Disease) reduced at least 75%.

NCT ID: NCT02062853 Completed - Actinic Keratoses Clinical Trials

Continuous Quality Improvement (CQI) Pilot Study Evaluating the Utility of an Educational Video

Start date: November 2012
Phase: N/A
Study type: Interventional

The primary aim of this study is to evaluate the effects of prospective patient education on patient satisfaction with administration of topical 5% 5-fluorouracil cream for the treatment of actinic keratosis involving the face, scalp, upper chest, dorsal hands and forearms. Specifically, this study aims to determine if prospective patient viewing of an educational video delineating treatment effects and expectations improves patient satisfaction and treatment completion rates.