Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)

Clinical Trial Description

Intralesional use by inject of adipose derived stem cells ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Keratopathy

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04147390` - Immunosuppression After Repeat Keratoplasty	Phase 2/Phase 3
Recruiting	`NCT04251143` - Dresden Corneal Disease and Treatment Study
Recruiting	`NCT03064984` - Blood Based Eyedrops From Different Sources in the Treatment of Severe Keratopathy	N/A
Completed	`NCT04917562` - Refractive Transepithelial Photo-keratectomy (T-PKR) in High Myopia

See also

Status

Clinical Trial

Phase

Recruiting

NCT04147390 - Immunosuppression After Repeat Keratoplasty

Phase 2/Phase 3

Recruiting

NCT04251143 - Dresden Corneal Disease and Treatment Study

Recruiting

NCT03064984 - Blood Based Eyedrops From Different Sources in the Treatment of Severe Keratopathy

N/A

Completed

NCT04917562 - Refractive Transepithelial Photo-keratectomy (T-PKR) in High Myopia

Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.

Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.

Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

NCT number	NCT01808378
Study type	Interventional
Source	Instituto de Investigación Hospital Universitario La Paz
Contact	Mariano García-Arranz, PhD
Phone	0034 912071022
Email	mgarciaa.hulp@salud.madrid.org
Status	Recruiting
Phase	Phase 2
Start date	February 2013
Completion date	December 2014

Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT) — HULPOFT

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms