Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy

Kennedy's Disease Clinical Trial

Official title: Effect of Goserelin (Zoladex®) in Spinal and Bulbar Muscular Atrophy in Thai Patients

Status Completed

Clinical Trial Summary

This is a therapeutic trial study to demonstrate whether Goserelin, a LHRH agonist has benefit in SBMA

Objective:

1. To study effects of Goserelin to clinical course of patients with spinal and bulbar muscular atrophy in Thailand

2. To demonstrate physiological and pathological changes in treated patients with Goserelin.

3. To assess tolerability and adverse effect of Goserelin therapy

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Atrophy
• Bulbo-Spinal Atrophy, X-Linked
• Kennedy's Disease
• Muscular Atrophy
• Muscular Disorders, Atrophic
• Spinobulbar Muscular Atrophy

• NCT number: NCT00851461
• Study type: Interventional
• Source: Ramathibodi Hospital
• Status: Completed
• Phase: Phase 4
• Start date: April 2008
• Completion date: November 2013