Effect of Electroacupuncture on Refractory Pain in Juvenile Rheumatoid Arthritis: Randomized Controlled Trial

Juvenile Rheumatoid Arthritis Clinical Trial

Official title:

Effect of Electroacupuncture Versus Phonophoresis on Refractory Pain in Juvenile Rheumatoid Arthritis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05504382
• Other study ID #: P.T.REC/012/003788
• Status: Recruiting
• Phase: N/A
• Start date: August 1, 2022
• Est. completion date: May 1, 2023

Study information

• Verified date: August 2022
• Source: Egyptian Chinese University
• Contact: Alaa Anwar, Ph.D
• Phone: +201002538439
• Email: Aalaa.anwar222[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

the purpose of the study is to investigate the effect of Electrical Acupuncture Versus naproxen phonophoresis on Refractory pain in Juvenile Rheumatoid arthritis

Description:

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and adolescents, affecting approximately one in 1000 children in North America. It is diagnosed in children younger than 16 years of age with arthritis in one or more joints for at least six weeks after other causes have been excluded. Arthritis in JIA is characterized by stiffness, pain and swelling of affected joints. The disease course of JIA may involve flares of increased disease activity or chronic persistent joint inflammation, even into adulthood. Various complications may arise secondary to ongoing disease activity or treatment, including joint damage and deformity, growth abnormalities and osteoporosis with fragility fractures The prevalence of refractory pain in children with arthritis is of particular concern because it often contributes to poor physical and psychosocial outcomes. Increased daily symptoms of pain predict considerable functional disability, including significantly reduced participation in school, social and physical activities, and augmented mood disturbance

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 42
• Est. completion date: May 1, 2023
• Est. primary completion date: November 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 14 Years to 16 Years

Eligibility

Inclusion Criteria:

• • Age ranges from 14 to 16 years.
• All children will be assigned to the study are suffering from persistent oligoarthritis.
• All children have regional knee pain complaint more than 6 weeks.
• Pain and stiffness especially in the morning, and a joint that feels warm to the touch
• Low grade fever at the onset of disease

Exclusion Criteria:

• • Neurological disorders.
• Dermatological disorders.
• Acute trauma prior to the study.
• Other co- morbidities like diabetes and conditions associated with inflammation such as malegnancies.
• Analgesic drugs or NSAIDs during the treatment period.

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Juvenile
• Arthritis, Rheumatoid
• Juvenile Rheumatoid Arthritis
• Pain, Intractable

Intervention

Device:
• naproxen phonophoresis
transmission of naproxen molecule by therapeutic ultrasound

Locations

Country	Name	City	State
Egypt	Cairo University	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Mohamed Abdelmoneim El Meligy

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	knee pain	change in refractory knee pain will be assessed by visual analogue scale	2 weeks
Secondary	knee joint range of motion	change in the range of motion of knee joint will be measured by universal goniometer	2 weeks