Juvenile Rheumatoid Arthritis Clinical Trial
Official title:
Research Registry for Juvenile Arthritis
Juvenile rheumatoid arthritis (JRA) is the most common chronic inflammatory disease in children, and may be related to genetics. Having two siblings who both have JRA in one family is rare. The purpose of this registry is to collect patient information and blood samples from qualifying JRA siblings and their families. The goal of the registry is to further understanding of JRA as related to genetics.
JRA is the most common chronic inflammatory pediatric rheumatic disease. JRA may be related to a complex genetic trait. It is rare to have two or more affected siblings, or sibpairs, within one family. The JRA ASP (Affected Sibpair) Registry is a nationwide effort and will collect information and blood samples from JRA sibpairs and their families. Unaffected family members (e.g., mother, father, and unaffected children) are also invited to participate. Patients and their families may enroll in the registry in one of two ways: patients may contact the registry directly, or they may be referred to the registry through their physician. Once the family has qualified to join the registry, the family will be asked to complete a questionnaire on the medical history of their JRA-affected members. Physicians of the JRA-affected members will be asked to complete questionnaires about their patients' conditions. Family members will also be invited to provide a one-time blood sample. Information collected through the registry will help researchers identify genes involved in JRA susceptibility. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00004420 -
Study of Gammalinolenic Acid for Juvenile Rheumatoid Arthritis
|
N/A | |
Recruiting |
NCT05545839 -
Transition to Adulthood Through Coaching and Empowerment in Rheumatology
|
N/A | |
Completed |
NCT00010335 -
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders
|
Phase 1 | |
Completed |
NCT00690573 -
Safety, Efficacy, and Pharmacokinetics of Adalimumab in Japanese Children With Juvenile Rheumatoid Arthritis
|
Phase 3 | |
Completed |
NCT00443430 -
Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis
|
Phase 4 | |
Completed |
NCT03780959 -
Safety and Efficacy of Etanercept (Recombinant Human Tumor Necrosis Factor Receptor Fusion Protein [TNFR:Fc]) in Children With Juvenile Rheumatoid Arthritis (JRA)
|
Phase 2/Phase 3 | |
Active, not recruiting |
NCT00006055 -
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases
|
N/A | |
Completed |
NCT00570934 -
Supplementation With Vitamin D, Calcium or Both on Calcium Absorption and Bone Mineral Content in Children With JRA
|
Phase 3 | |
Recruiting |
NCT05715463 -
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
|
N/A | |
Completed |
NCT00289094 -
Randomized Fixed Bearing vs Mobile Bearing Cruciate Retaining TKA
|
N/A | |
Terminated |
NCT00078806 -
Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis
|
Phase 3 | |
Completed |
NCT00078793 -
Registry of Etanercept (Enbrel®) In Children With Juvenile Rheumatoid Arthritis
|
N/A | |
Completed |
NCT00000429 -
Calcium Supplements for Bone Health in Juvenile Rheumatoid Arthritis
|
Phase 2 | |
Completed |
NCT01044823 -
Use of Thermal and 3D Imaging to Quantify Arthritis
|
N/A | |
Terminated |
NCT00029042 -
Infliximab to Treat Children With Juvenile Rheumatoid Arthritis
|
Phase 2 | |
Withdrawn |
NCT00286689 -
Effects of Growth Hormone in Chronically Ill Children
|
N/A | |
Completed |
NCT00095173 -
BMS-188667 in Children and Adolescents With Juvenile Rheumatoid Arthritis
|
Phase 3 | |
Completed |
NCT00001862 -
TNRF:Fc to Treat Eye Inflammation in Juvenile Rheumatoid Arthritis
|
Phase 2 | |
Not yet recruiting |
NCT05114343 -
Effectiveness and Feasibility of a Home-based Exercise Program for Adolescents With Juvenile Idiopathic Arthritis
|
N/A | |
Terminated |
NCT03781375 -
Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis
|
Phase 3 |