Juvenile Idiopathic Arthritis Clinical Trial
Official title:
Chronic Non-inflammatory Pains in Rheumatopediatrics
The purpose of this study is to determine the frequency of chronic pain in adolescent with
juvenile idiopathic arthritis, especially when the disease is inactive or with minimal
activity.
Secondary objectives are, first to determine intensity of pain and its repercussion in daily
life and second to determine risk factor of chronic pain.
Juvenile idiopathic arthritis is the most frequent pathology in paediatric rheumatology
clinic. Pain is an important symptom in paediatric rheumatology. It is actually poorly
studied and is not evaluate in disease activity score like the Juvenile Arthritis Disease
Activity Score (JADAS). It is source of handicap, social and psychological distress and
greatly contribute to poor quality of life. Chronic pain is frequently multifactorial, even
in inflammatory disease. In adult population, rheumatologists have shown an association
between inflammatory disease like spondylarthritis or rheumatology polyarthritis and
fibromyalgia.
There is no specific data on chronic pain in juvenile idiopathic arthritis. Pain is mostly
evaluated by the Visual Analogue Scale (VAS) with no evaluation of pain repercussion on daily
life or its chronicity. This study's primary objective is to determine the frequency of
chronic pain and its relationship with disease activity. Secondaries objectives are to
determine repercussion of pain in daily life, and risk factor of chronic pain.
To responded to this objective, we will conduct a transversal study in a paediatric
rheumatology refence centre in Necker-Enfants malades Hospital. We will include all patients
between 12 and 18 years old followed in our centre for any type of juvenile idiopathic
arthritis.
Patients will be evaluated as usual by their paediatrics rheumatologist during a follow-up
consultation or hospitalisation with the used of the clinical JADAS. Patient accepting to
participate the study will be given a paper questionnaire evaluating chronic pain, its
repercussion, anxiety (by the used of the Revised Children's Manifest Anxiety Scale (RCMAS
score)), depression (by the used of the Children's Depression Inventory (CDI score)),
Sleepiness (by the used of the Pediatric Daytime Sleepiness Scale (PDSS score)) and quality
of life (by the used of the measurement model for the Pediatric Quality of Life inventory
(PedQL score)).
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