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The Effect of Creatine Supplementation on Muscle Function in Childhood Myositis

Juvenile Dermatomyositis Clinical Trial

Official title:
The Effect of Creatine Supplementation on Muscle Function in Childhood Myositis

Clinical Trial Summary

This project will bring together a multidisciplinary team of pediatric rheumatologists, neurologists, metabolic geneticists and exercise physiologists to determine the effect of creatine (CR) supplementation on muscle function and muscle metabolism in children with Dermatomyositis (DM). The investigators propose using well-established exercise testing techniques as well as new, powerful exercise imaging protocols in order to better delineate the effects of CR on muscle pathophysiology in a non-invasive way. Evidence from this study will provide information regarding the effect of creatine supplementation on muscle function in DM. Improvements in muscle function and fatigue through CR use may also contribute to an improvement in quality of life and have significant clinical implications for the treatment of children with DM.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02267005
Study type Interventional
Source The Hospital for Sick Children
Contact
Status Completed
Phase N/A
Start date March 2015
Completion date May 2017
View Details
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