Jugular Venous Flow Healthy Volunteers

Jugular Venous Blood Flow Clinical Trial

Official title:

Effect of Different Surgical Positions on the Cerebral Venous Drainage: an Ultrasound Study on Healthy Volunteers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02002494
• Other study ID #: 13-6244-BE
• Status: Completed
• Start date: June 2013
• Est. completion date: February 2014

Study information

• Verified date: May 2020
• Source: University Health Network, Toronto
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow in the between right and left internal jugular veins in park bench position, particularly there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine position.

Description:

The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.

Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 27
• Est. completion date: February 2014
• Est. primary completion date: February 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult healthy volunteers who are above the age of 18

• American Society of Anesthesiologists classification (ASA) 1

• Body mass index (BMI) less than and equal to 35

Exclusion Criteria:

• ASA 2 and above

• BMI above 35

• Lack of informed consent

• Language barrier

• Medical students and anaesthesia residents going through the department as part of their rotation

Related Conditions & MeSH terms

• Jugular Venous Blood Flow

Intervention

Other:
• Different positions
Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench

Locations

Country	Name	City	State
Canada	University Health Network, Toronto Western Hospital	Toronto	Ontario

Sponsors (1)

Lead Sponsor	Collaborator
University Health Network, Toronto

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Internal Jugular Venous (IJV) Cross Sectional Area	Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions.	1 day
Primary	Right and Left IJV Cross Sectional Area	Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench	1 day
Primary	Internal Jugular Venous (IJV) Doppler Velocity	27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions	1 day
Primary	Bilateral Internal Jugular Vein (IJV) Flow	Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) .	1 day
Primary	Bilateral Internal Jugular Vein (IJV) Doppler Velocity	Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position.	1 day
Primary	R IJV and L IJV Flow	Bilateral internal jugular vein (IJV) flow between supine and right park bench position.	1 day