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Clinical Trial Details — Status: Withdrawn

Administrative data

NCT number NCT00664651
Other study ID # 2006541
Secondary ID
Status Withdrawn
Phase N/A
First received April 21, 2008
Last updated April 22, 2015
Start date December 2006
Est. completion date April 2015

Study information

Verified date April 2015
Source Ottawa Hospital Research Institute
Contact n/a
Is FDA regulated No
Health authority Canada: Ethics Review Committee
Study type Observational

Clinical Trial Summary

Our primary research question is to find out whether there is a genetic component to the development of joint contractures following knee surgery, through the application of lab techniques.


Description:

After total knee replacement surgery, some people develop joint stiffness, which is also called a joint contracture. Contractures cause the envelope of the knee (called the capsule) to stiffen and become rigid so the patient can no longer move their knee the way they used to. After stretching and other exercises, only a surgery can try and divide or remove the contracture. The main purpose of this research is to study the cause of the contracture and specifically if certain people are predisposed to contractures.


Recruitment information / eligibility

Status Withdrawn
Enrollment 0
Est. completion date April 2015
Est. primary completion date April 2015
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

-knee contractures post arthroplasty scheduled for arthrotomy with debridement of capsular tissue Controls will be patients scheduled for arthrotomy with debridement of capsular tissue for the other reasons(primary knee arthroplasty, ORIF of the knee secondary to trauma, ACL repair, amputation, elective joint arthroplasty with capsuloplasty etc.)

Exclusion:

- transmissible disease (HIV, Hep B,C)

- confirmed or suspected neoplasia

- suspected infection

Study Design

Observational Model: Case Control, Time Perspective: Retrospective


Related Conditions & MeSH terms


Locations

Country Name City State
Canada Ottawa Hospital Research Institute Ottawa Ontario

Sponsors (1)

Lead Sponsor Collaborator
Ottawa Hospital Research Institute

Country where clinical trial is conducted

Canada, 

Outcome

Type Measure Description Time frame Safety issue
Primary Gene expression Dec 2015 No
See also
  Status Clinical Trial Phase
Recruiting NCT06042907 - Development, Validation, and Evaluation of a Risk Assessment Tool for Contractures: the ORACLE Study
Completed NCT02878941 - Synovial Fluid Analysis of Intraarticular Elbow Fracture N/A