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Jaundice, Neonatal clinical trials

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NCT ID: NCT06386731 Completed - Neonatal Jaundice Clinical Trials

Continuous Versus Intermittent Phototherapy in Treatment of Neonatal Jaundice

Start date: July 5, 2022
Phase: N/A
Study type: Interventional

One of the most common diseases in the neonatal period is indirect hyperbilirubinemia (IHB). After phototherapy was discovered accidentally in 1958, it has been used as the most effective treatment method for IHD for more than 60 years. Sources that provide phototherapy are developing rapidly technologically. However, there is no clearly defined usage table in the literature for applying phototherapy with faster effects and fewer side effects. In recent years, the use of intermittent phototherapy has been recommended with similar effectiveness. Phototherapy has significant side effects such as dehydration, diarrhea, chromosome breaks, retinal damage, skin rashes, hypocalcemia, thrombocytopenia. As phototherapy exposure decreases, its side effects decrease.In our study; We plan to find the most ideal method in the treatment of IHB by comparing intermittent PT with continuous phototherapy in terms of effectiveness. We aim to achieve the best bilirubin reduction and minimal side effects with less exposure to phototherapy.

NCT ID: NCT06372093 Completed - Jaundice, Neonatal Clinical Trials

Evaluation of Bilirubin Measurements in Newborns From Smartphone Digital Images in a Population in Botswana

Start date: March 16, 2023
Phase: N/A
Study type: Interventional

The general objective of this study is to evaluate the accuracy of a novel smartphone application for jaundice screening (Picterus Jaundice Pro) in a population with high melanin content in the skin. The specific objectives for this study are: i. To assess the correlation between bilirubin level measurements obtained by Picterus Jaundice Pro with Total Serum Bilirubin (TSB), and TcB, in newborns with high melanin content in the skin. ii. To determine the accuracy of Picterus Jaundice Pro in newborns with high melanin content in the skin.

NCT ID: NCT06227624 Completed - Neonatal Jaundice Clinical Trials

Role of Oral Zinc in Reducing Neonatal Indirect Hyperbilirubinemia

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

This study aimed to determine the role of oral zinc in reducing the neonatal indirect hyperbilirubinemia if used concomitant with the standard phototherapy

NCT ID: NCT05692648 Completed - Newborn Jaundice Clinical Trials

Effect of Repositioning Frequency Neonates Receiving Phototherapy

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

Purpose: The present study was conducted to determine the effect of repositioning frequency during phototherapy on bilirubin level and neonates comfort. Design and methods: This was a single-centered, single-blind, 3-arm, pretest-posttest parallel-group randomized controlled trial conducted in a neonatal intensive care unit. Participants were randomly assigned to one of three groups: Supine position group (n = 20), hourly position change group (n = 20), and control group (n = 20). The bilirubin level and comfort levels of the neonates were evaluated.

NCT ID: NCT05650463 Completed - Jaundice, Neonatal Clinical Trials

Evaluation of a Smartphone-based Screening Tool (Picterus Jaundice Pro) for Neonatal Jaundice in Dark Skin Newborns

Start date: November 29, 2021
Phase: N/A
Study type: Interventional

A cross-sectional study at the Södersjukehuset facility (Stockholm, Sweden) collect data of newborns from a population with Neomar scale type 4 to adjust the algorithm of Picterus JP

NCT ID: NCT05625880 Completed - Jaundice, Neonatal Clinical Trials

Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Nepali Population

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

This cross-sectional study evaluates the accuracy of a novel smartphone application that estimates bilirubin levels in newborns at Dhulikhel Hospital, Kathmandu Nepal.

NCT ID: NCT05623553 Completed - Jaundice, Neonatal Clinical Trials

Evaluation of a Smartphone Based Diagnostic Tool to Assess Neonatal Jaundice in a Mexican Population

Start date: July 1, 2018
Phase: N/A
Study type: Interventional

This corss-sectional study aims to test the performance and accuracy of the Picterus JP screening device in newborns with different skin types.

NCT ID: NCT05616845 Completed - Jaundice, Neonatal Clinical Trials

A mHealth Application as a Screening Tool for Neonatal Jaundice in Filipino Neonates

Start date: February 2, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to test the reliability of the Picterus smartphone application in Filipino neonates. A descriptive cross-sectional study will be the method to understand the correlation of the modalities and to determine the reliability of the application

NCT ID: NCT05167474 Completed - Newborn Jaundice Clinical Trials

Influence of Breast Milk Smell on Newborns Bilirubin Level, Duration of Time Phototherapy and Comfort in Newborns Receiving Phototherapyv

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

ABSTRACT Purpose: This research was done for the purpose of determining the impact of breast milk smell administered to term infants hospitalized in neonatal intensive care units (NICU) due to physiological jaundice on their bilirubin levels, length of remaining in phototherapy and comfort. Material and Method: It is an experimental, randomisation, controlled research. Target population of the research consisted of a total of 72 term infants who were hospitalized in the NICU of Bilecik Bozuyuk Public Hospital and met the sample selection criteria. Our research includes two groups. Breast milk smell group and control group. The infants were assigned to the groups via randomization method. Sample assignment to the groups was performed using stratification and blocking methods. The infants meeting the research sample selection criteria were stratified according to their postnatal age and then assigned to each group equally (blocking) by lot. However, two infants in the control group were excluded from the research at the request of their parents as the research continued. Thus, the research was completed with a total of 72 infants; 37 in the breast milk smell group and 35 in the control group. In the research, the data were collected using "Personal Data Collection Form", "Phototherapy Follow-up Chart" and "Neonatal Comfort Behavior Scale". The data were analyzed using the SPSS (Statistical Package for Social Sciences) 21.0 (IBM corp. Relased 2012. IBM SPSS Statistics for Windows, version 21.0 Armonk, NY: IBM corp.) package software.

NCT ID: NCT05121311 Completed - Newborn Jaundice Clinical Trials

Assessment of Neonatal Hyperbilirubinemia by NeoprediX B.1 Algorithm

Bili-PrediX1
Start date: August 9, 2021
Phase:
Study type: Observational

Due to actual standard of neonatal care bilirubin is monitored in neonates several times after birth to avoid hyperbilirubinemia. As the peak is often one or two days after discharge from hospital a more precise predication than the actual one is desirable to avoid needlessly follow-ups. The precision of an algorithm to predict bilirubin values 24-48h into the future is evaluated in this study.