Ovarian Reserve and Embryo Implantation

IVF Clinical Trial

— IRO  

Official title:

Ovarian Reserve and Embryo Implantation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03989921
• Other study ID #: Local/2018/OP-01
• Status: Completed
• Start date: November 29, 2018
• Est. completion date: April 30, 2019

Study information

• Verified date: June 2019
• Source: Centre Hospitalier Universitaire de Nimes
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Compare, in young patients with In vitro fertilization (IVF), the rate of embryo implantation by early culture transfer (J2-J3) between 2 groups of patients: "normo responders" vs. "poor responders".

Recruitment information / eligibility

• Status: Completed
• Enrollment: 598
• Est. completion date: April 30, 2019
• Est. primary completion date: April 30, 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 35 Years and older

Eligibility

Inclusion Criteria:

• IVF patient managed with or without ICSI between 01/01/2014 and 30/06/2015 in one of the two study centres

• Age < 35 years old

• Fresh transfer of at least one embryo between D2 and D6

• patients who have already received one or more transfer attempts.

Exclusion Criteria:

• No fresh transfer (Freeze All, segmentation failure, stimulation failure)

• Double successive embryo transfer (e. g. J3-J5). We did not retain these cases because if only one of the 2 embryos is implanted, it is not possible to know which transfer it corresponds to.

• Maternal serum FSH determination < 4 IU/ml at D3 in the baseline balance sheet (hypogonadotropic hypogonadism)

Related Conditions & MeSH terms

• IVF
• Ovarian Reserve

Intervention

Other:
• no intervention. observational study
no intervention. observational study

Locations

Country	Name	City	State
France	CHUNimes	Nîmes

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nimes

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The embryo implantation rate at 5 weeks after transfer is defined by the presence of an embryo with objective cardiac activity by ultrasound	The embryo implantation rate corresponds to the number of embryos with cardiac activity found on the number of embryos transferred	5weeks