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Isotonic Saline clinical trials

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NCT ID: NCT04672382 Completed - Morphine Clinical Trials

Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to the effect of opioid (morphine) intradermal application on histaminergic and non-histaminergic itch. In particular, we would like to demonstrate that also peripheral administration of morphine may affect mast cell release of histamine.

NCT ID: NCT04439994 Completed - Hypertonic Saline Clinical Trials

Activation of miRNA and Proteins After Acute Experimental Pain. (miRNA: Micro RNA)

miRNA
Start date: November 1, 2020
Phase: N/A
Study type: Interventional

In this experiment, the investigators would like to test the following: 1. Does acute pain induced by hypertonic injection cause changes in plasma miRNA and protein expression ? 2. Can these canges correlate with the development of local hyperalgesia? 3. How does the plasma miRNA expression change over a duration of 24 hours post pain induction ? 4. Which mRNA targets are potentially affected by acute pain?

NCT ID: NCT04146311 Completed - Knee Pain Chronic Clinical Trials

Effect of Short-term Motor Training on Accuracy and Precision of Knee Movement in Human With and Without Knee Pain

Start date: October 30, 2019
Phase: N/A
Study type: Interventional

The objects of this research are to investigate the ability of the motor learning and test the possible differences between younger and older healthy human, and between non-pain and acute experimental pain and chronic clinical pain conditions.