Ischemic Cardiomyopathy Clinical Trial
This study will collect clinical, echocardiographic, nuclear imaging and hemodynamic data in a group of patients with end stage ischemic cardiomyopathy undergoing left ventricular assist device (LVAD) implantation to investigate the incidence of recovery of myocardial function when supported with LVADs, and to study the association between hibernating myocardium and myocardial recovery in this population.
Clinical, echocardiographic and hemodynamic data will be obtained from the patients' medical records. Assessment of viability will be performed using a Tl-201 Rest-Redistribution Scintigraphy protocol within 2 weeks before LVAD implantation and 2 months after LVAD implant. Recovery of myocardial function will be assessed using available 2D transthoracic echocardiographic images and with the novel imaging modality, Speckle Tracking Echocardiography (STE), in order to provide a regional quantification of the myocardium, in the context of TL-201 results. Transthoracic echocardiograms will be performed 2 weeks prior to the LVAD implant and 1, 2, 3, 4, 6, 9, and 12 months after implantation. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04066738 -
Scar Location and Acute Haemodynamic Response to MultiPoint Pacing Study in Patients With Ischemic Cardiomyopathy
|
N/A | |
| Recruiting |
NCT03536052 -
Ablation at Virtual-hEart pRedicted Targets for VT
|
N/A | |
| Enrolling by invitation |
NCT02930265 -
Clinical Study of Liraglutide in Improving Cardiac Function for Patients With Ischemic Cardiomyopathy
|
N/A | |
| Completed |
NCT01215253 -
Ranolazine Implantable Cardioverter-Defibrillator Trial
|
Phase 3 | |
| Completed |
NCT04508608 -
Scintigraphic Evaluation of Contractile and Coronary Reserve in Patients With Ischemic Cardiomyopathy
|
||
| Recruiting |
NCT05888662 -
Endo-epicardial vs Endocardial-only Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy (EPIC-VT)
|
N/A | |
| Completed |
NCT03857906 -
Evaluation of Prophylactic Use of a Preoperative IABP in High-Risk Coronary Artery Bypass Graft Surgery
|
||
| Completed |
NCT02501811 -
Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure
|
Phase 2 | |
| Recruiting |
NCT02058771 -
Utilising Lifemap to Investigate Malignant Arrhythmia Therapy
|
||
| Not yet recruiting |
NCT01946048 -
Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Ischemic Cardiomyopathy
|
Phase 1 | |
| Terminated |
NCT01759212 -
Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure.
|
Phase 2/Phase 3 | |
| Not yet recruiting |
NCT01447069 -
Use of Beta-agonists in Stable Severe Congestive Heart Failure
|
N/A | |
| Recruiting |
NCT00972114 -
CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy
|
Phase 1/Phase 2 | |
| Completed |
NCT00896142 -
Optima Coronary Artery Disease (CAD) (Optimal Mechanical Evaluation)
|
N/A | |
| Recruiting |
NCT01076660 -
Left Ventricular Structural Predictors of Sudden Cardiac Death
|
||
| Completed |
NCT00305214 -
MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients
|
N/A | |
| Completed |
NCT00305240 -
MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients
|
N/A | |
| Active, not recruiting |
NCT00962364 -
Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease
|
||
| Recruiting |
NCT05769036 -
Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients
|
N/A | |
| Completed |
NCT03862339 -
The SoundScar Study The SOUNDSCAR Study
|