2D Perfusion DSA for the Quantification of Infrapopliteal Angioplasty

Ischemia Limb Clinical Trial

Official title:
Feasibility of 2D Perfusion DSA With Custom-made, Color-coded Software for the Quantification of Foot Perfusion Following Infrapopliteal Angioplasty

Status Completed

Clinical Trial Summary

A custom-made, 2D-perfusion digital subtraction angiography (PDSA) algorithm has been designed and implemented towards foot perfusion quantification following endovascular treatment of critical limb ischemia (CLI), in order to assist intra-procedural decision-making and enhance clinical outcomes.

Clinical Trial Description

This is a prospective, single-center, study investigating the feasibility of 2D-PDSA using newly-developed, non-commercially available, color-coded software for the quantification of foot perfusion following infrapopliteal angioplasty for the treatment of CLI. In total, 7 consecutive patients scheduled to undergo infrapopliteal endovascular treatment of CLI were enrolled. Perfusion Blood Volume (PBV), Mean Transit Time (MTT), and Perfusion Blood Flow (PBF) maps were extracted by analyzing Time-Intensity Curves and signal intensity on the perfused vessel mask. Mean values calculated from user-specified ROIs on perfusion maps were employed to evaluate the patient's pre- and post- endovascular treatment condition. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04356092
Study type	Interventional
Source	Attikon Hospital
Contact
Status	Completed
Phase	N/A
Start date	May 2, 2017
Completion date	July 14, 2019

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