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ConfocAl endomicroSCopy bAsed Diet Trial in IBS — CASCADE  

Irritable Bowel Syndrome Clinical Trial

Official title:
Targeted Elimination Diet in IBS Patients Following Identification of Trigger Nutrients Using Confocal Laser Endomicroscopy

Clinical Trial Summary

After a thorough baseline evaluation, IBS patients will be exposed to nutrients while undergoing confocal laser endomicroscopy (CLE). Patients presenting an acute mucosal reaction upon nutrient exposure will be instructed to exclude their respective trigger nutrient or a nutrient without mucosal reaction (=sham diet) from their diet for 4 weeks in a randomized, blinded crossover fashion. The aim of the trial is to assess the symptomatic response to the targeted diet and further elucidate mechanisms underlying the acute mucosal reactions observed in CLE upon nutrient exposure.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05097872
Study type Interventional
Source Universitaire Ziekenhuizen Leuven
Contact Lukas M Balsiger, MD
Phone +32 16 37 70 90
Email lukasmichaja.balsiger@kuleuven.be
Status Recruiting
Phase N/A
Start date October 19, 2021
Completion date October 2023
View Details
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