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NCT00925223 Clinical Trial

Brain-derived Neurotrophic Factor Participates in Visceral Hyperalgesia in Irritable Bowel Syndrome (IBS) Patients

Irritable Bowel Syndrome Clinical Trial

Official title:
Study of Brain-derived Neurotrophic Factor in Visceral Hyperalgesia in IBS Patients

Clinical Trial Details — Status: Enrolling by invitation

Administrative data
NCT number NCT00925223
Other study ID # 2009SDU-QILU-G02
Secondary ID NSFC30570831
Status Enrolling by invitation
Phase N/A
First received June 18, 2009
Last updated October 13, 2009
Start date June 2009
Est. completion date November 2009

Study information
Verified date October 2009
Source Shandong University
Contact n/a
Is FDA regulated No
Health authority China: Ethics Committee
Study type Observational

Clinical Trial Summary

Brain-derived neurotrophic factor (BDNF), originally known to be a member of the nerve growth factor family, has aroused attention as a modulator in visceral hyperalgesia recently. Visceral hypersensitivity is recognized as a clinical hallmark in IBS patients. So in this study, the investigators will focus on the role of BDNF in colonic hyperalgesia in IBS patients.

Recruitment information / eligibility
Status Enrolling by invitation
Enrollment 30
Est. completion date November 2009
Est. primary completion date August 2009
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients diagnosed with irritable bowel syndrome.

Exclusion Criteria:

- Patients have similar clinical symptoms as IBS, yet there is morphologic changes in the intestine.

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Shandong University
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