Irreversible Pulpitis Clinical Trial
Official title:
Effect of Ketorolac Premedication on Anesthetic Efficiency of Inferior Alveolar Nerve Block, Pre-Treatment and Post-Endodontic Pain in Teeth With Irreversible Pulpitis: A Randomized Controlled Double Blinded Trial
The aim of this study to assess effect of ketorolac premedication on the effectiveness of the inferior alveolar nerve block, pretreatment and postoperative pain in patients with symptomatic irreversible pulpitis.
- Patients will be clinically and radiographically examined and their eligibility will be
assessed and preoperative pain will be measured. Eligible patients will be treated in
one visit.
- Patients will be randomly assigned to one of 2 groups: experimental group (taking a 10
mg tablet of ketorolac) and the control group (taking a placebo tablet). Each tablet
will be taken one hour before starting treatment. The patient's pain will be assessed
before local anesthetic adminstration. After 15 minutes of the initial inferior
alveolar nerve block (IANB), the teeth will be examined using a cold pulp sensitivity
test; in case of no or mild pain, the treatment will be initiated.
- During root canal treatment, no to mild pain response will be considered success. In
case of failure, supplemental anesthesia will be administrated.
- Postoperative pain will be assessed 6, 12, 24 and 48 hours after treatment. The number
of patients who will require rescue analgesic medication within the 48 hours
postoperatively will be counted.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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