Pulpotomy as a Treatment of Irreversible Pulpitis

Status Enrolling by invitation

Clinical Trial Summary

The procedure currently recommended for the treatment of irreversible pulpitis is the endodontic treatment, i.e. the complete elimination of the pulp, disinfection and obturation of the whole root canal system. The emergency procedure consists of a pulpotomy, followed at an ulterior appointment by the root canal treatment. The purpose of the present pilot study is to evaluate the feasibility of performing the pulpotomy as a permanent treatment in mature molars. If hemostasis can be achieved after removing the coronal part of the pulp, a tricalcium silicate cement will be directly applied on the remaining pulp at the root canal entrances. A short-term follow-up will be performed at one week by evaluating the pain relief of the patient. Long-term success will then be evaluated every year by verifying the absence of periapical radiolucency on the x-ray as well as the absence of clinical symptoms and signs. A standard root canal procedure will serve as control. During the pulpotomy treatment, blood sample with microcapillary will be performed. We will analyze a ratio of pro-inflammatory and anti-inflammatory cytokines.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02920606
Study type	Interventional
Source	Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact
Status	Enrolling by invitation
Phase	N/A
Start date	April 2016
Completion date	June 2024

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT04585438` - Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial	Phase 4
Completed	`NCT02923687` - Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain	Phase 2
Completed	`NCT02601911` - Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection	Phase 2
Completed	`NCT02614118` - Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain	Phase 2
Completed	`NCT01496846` - Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars	Phase 4
Withdrawn	`NCT04040127` - Residual Dental Pulp Tissue and Cord Blood Stem Cells	Phase 2
Completed	`NCT06176378` - A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth	N/A
Recruiting	`NCT04243733` - MTA vs CEM Pulpotomy in Young Permanent Molars	N/A
Recruiting	`NCT06245161` - Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients	N/A
Not yet recruiting	`NCT04573374` - Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial	N/A
Completed	`NCT05778227` - Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.	N/A
Completed	`NCT04654845` - Patient Perception Between Two Emergency Treatments of Symptomatic Irreversible Pulpitis.	N/A
Recruiting	`NCT06142799` - Influence of Moment of Restoration in Pain After a Root Canal Treatment	N/A
Active, not recruiting	`NCT06240130` - Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents	N/A
Not yet recruiting	`NCT05349929` - Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran)	Phase 2
Recruiting	`NCT06149845` - Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis	N/A
Completed	`NCT01561183` - Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis	N/A
Recruiting	`NCT06231290` - The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth	N/A
Not yet recruiting	`NCT05277246` - Effect of Using Different Concentrations of NaOCI on IL-8 Level	N/A
Completed	`NCT06081335` - Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial	N/A