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Irreversible Pulpitis clinical trials

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NCT ID: NCT06433245 Recruiting - Clinical trials for Irreversible Pulpitis

Outcome Following Use of Different Concentrations of NaOCl as Wound Lavage and Hemostatic Agent in Partial Pulpotomy

Start date: May 23, 2024
Phase: N/A
Study type: Interventional

The aim of this randomised control trial is to compare the effect of different concentrations of NaOCl on outcome of partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis. The main question it aims to answer are: 1. clinical and radiographic outcome of partial pulpotomy following use of 5% and 3% NaOCl in mature permanent teeth with clinical signs indicative of irreversible pulpitis. 2. OHRQoL and pain experience after use of 5% and 3% NaOCl during partial pulpotomy in teeth with clinical signs indicative of irreversible pulpitis.

NCT ID: NCT06358833 Recruiting - Postoperative Pain Clinical Trials

Comparison of Endodontic Postoperative Pain Using Different Irrigation Systems

Start date: April 15, 2024
Phase: N/A
Study type: Interventional

Summary: After a root canal procedure, it is common to experience postoperative pain. Cleaning the root canal thoroughly is crucial for pain relief, but removing all debris with standard methods is difficult. Irrigation, using either traditional endodontic needles or newer methods like endodontic activation, helps clean the canal. This study aims to compare pain levels after using conventional needles versus an Endo1 Ultrasonic Endo Activate Device for irrigation. Patients will undergo standard root canal preparation and then be randomly assigned to one of two groups for final irrigation: the Endo1 device (EA) and the conventional endodontic needles (EN). The study will provide insights into which method is more effective in reducing postoperative pain.

NCT ID: NCT06245161 Recruiting - Clinical trials for Irreversible Pulpitis

Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.

NCT ID: NCT06231290 Recruiting - Clinical trials for Irreversible Pulpitis

The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The goal of this interventional randomized clinical trial is to test the effect of magnification and clinical experience of the operator on the success rate of full pulpotomy in mature adult molar teeth. The main questions it aims to answer are: - Does the use of magnification raise the success rate of full pulpotomy of mature adult molars? - Does the clinical experience of the operator dentist raise the success rate of full pulpotomy of mature adult molars? Participants will be asked to do the following: - Receive the pulpotomy treatment of their target molar tooth. - Record the pain score in the pain assessment chart. - Attend the follow-up visits. They'll receive a full pulpotomy treatment of their target molar tooth. Researchers will evaluate the usage of magnification in performing the pulpotomy procedure of adult molar teeth by postgraduate or undergraduate operators in comparison to performing the same pulpotomy procedure without magnification to see if it raises the overall success rate of pulpotomy.

NCT ID: NCT06194773 Recruiting - Clinical trials for Irreversible Pulpitis

The Effect of Totalfil and Neosealer Sealers on the Post-endodontic Pain

Start date: June 26, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effect of Totalfil and Neosealer sealers on post-endodontic pain compared to AH plus sealer in mandibular molars with symptomatic irreversible pulpitis. The main question: do Totalfil and Neosealer sealers affect postoperative pain intensity after root canal treatment in mandibular molars with symptomatic irreversible pulpitis? Participants will undergo root canal treatment using totalfil, Neosealer, or AH-Plus sealer. Researchers will compare Totalfil, Neosealer, and AH-Plus to assess the intensity of post-endodontic pain.

NCT ID: NCT06194721 Recruiting - Clinical trials for Irreversible Pulpitis

The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain

Start date: June 6, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the effect of cooling of local anesthesia on intraoperative pain during root canal treatment in mandibular molars diagnosed as symptomatic irreversible pulpitis. The main question it aims to answer is: Is there a difference in intra-operative pain levels using intra-pulpal anesthesia with and without cryotherapy during root canal treatment? Participants will undergo root canal treatment using intrapulpal anesthesia with and without cooling. Researchers will compare cold and room temperature intrapulpal anesthesia to see the intensity of intraoperative pain.

NCT ID: NCT06149845 Recruiting - Clinical trials for Irreversible Pulpitis

Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis

Start date: March 21, 2024
Phase: N/A
Study type: Interventional

This is a clinical trial to assess the treatment outcomes of pulpotomy in vital primary molars diagnosed with symptomatic irreversible pulpitis. Pulpotomy is a more conservative treatment option over the conventional pulpectomy treatment. Compared to pulpectomy, pulpotomy is a technically simpler procedure, less time consuming, easier for young patients to tolerate, and retains the proprioceptive sensation of the tooth - all important advantages when treating young children.

NCT ID: NCT06142799 Recruiting - Clinical trials for Irreversible Pulpitis

Influence of Moment of Restoration in Pain After a Root Canal Treatment

Start date: November 14, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare immediate placement of an overlay after root canal treatment with delayed placement of the overlay leaving the tooth one week in infra occlusion. The main question it aims to answer are: type of study: clinical trial participant population/health conditions: patients more that 18 years old who need a root canal treatment in posterior teeth with antagonist teeth. question 1: postoperative pain after 6 hours question 2: postoperative pain after 12 hours question 3: postoperative pain after 24 hours question 4: postoperative pain after 48 hours question 4: postoperative pain after 72 hours If there is a comparison group: Researchers will compare immediate overlay placement and delayed (1 week) overlay placement after root canal treatment to see if there is more pain in one group than in the other.

NCT ID: NCT05811403 Recruiting - Clinical trials for Irreversible Pulpitis

Epigallocatechin Gallate (EGCG) as a Flushing Agent During Full Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis

Start date: July 1, 2023
Phase: N/A
Study type: Interventional

This study evaluates the effect of two flushing agents (epigallocatechin gallate (EGCG) and sodium hypochlorite (NaOCl)) during full pulpotomy using two different calcium silicate-based materials (MTA and premixed bioceramic putty) on postoperative pain, success rate and dentin bridge thickness in mature permanent mandibular molars with irreversible pulpitis. Participants will be divided into four groups based on the flushing fluid and the pulp capping material to be used.

NCT ID: NCT05761730 Recruiting - Clinical trials for Irreversible Pulpitis

Oral Dexamethasone for the Management of Symptomatic Irreversible Pulpitis Without Performing Pulpotomy

Start date: February 15, 2023
Phase: Phase 1
Study type: Interventional

The efficacy of short course orally administered dexamethasone on the reduction of pain before conventional pulpotomy has not yet been demonstrated. Therefore, the aim of this randomized clinical study is to assess the effect of dexamethasone on the reduction of pain in mandibular molars with irreversible pulpitis, without performing conventional pulpotomy in comparison to pain following pulpotomy.