Clinical Trials Logo

Clinical Trial Summary

The aim of the study is to present the effect of implanting intrastromal fresh corneal lenticule by SMILE surgery as a new method-approach to correct the corneal shape on purpose to reduce irregular astigmatism and increasing visual acuity after penetrating keratoplasty.


Clinical Trial Description

Irregular astigmatism occurs when the curvature of the eye is pronounced in any direction, not just the center. The curve could be steeper towards the bottom than on top, or it could be any configuration in which the eye's surface area is uneven. Irregular astigmatism usually can result from corneal degenerations(keratoconus,pellucid marginal degeneration,keratoglobus), corneal surgery or trauma. Irregular astigmatism is still the main cause of decreased visual acuity after penetrating keratoplasty. Our study present new therapeutic method and new technology to manage irregular astigmatism after PK. Knowing that the incidence of high and irregular astigmatism after PK is still a frequent complication and source of frustration for patients and corneal surgeons our study present an adequate surgical technique implanting intrastromal human corneal lenticule using SMILE for treatment of corneal irregular astigmatism after PK trying satisfy patients visual expectations. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04987060
Study type Interventional
Source Eye Hospital Pristina Kosovo
Contact
Status Active, not recruiting
Phase N/A
Start date March 1, 2017
Completion date December 1, 2024

See also
  Status Clinical Trial Phase
Completed NCT02444923 - Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders N/A
Recruiting NCT06256770 - Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
Completed NCT03140046 - Visual Outcomes of Topography Guided Photorefractive Keratectomy (PRK) for Treatment of Patients With Irregular Cornea N/A
Recruiting NCT05574270 - Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas N/A
Active, not recruiting NCT04698590 - Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism N/A
Recruiting NCT02894489 - Changes of Visual Function, Ocular Surface Structures and Physiology After Long-Termed Contact Lens Wear N/A