Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants

Status Completed

Clinical Trial Summary

Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth. Compared with early clamping, a delay of around 2-3 min provides an additional 25-40 mL of blood per kg of bodyweight.

The results of previous intervention studies on delayed clamping are mixed, and few followed up infants beyond the perinatal period. All longer follow up studies have been performed in low income countries. The main objectives, therefore, was to assess whether delayed cord clamping improves hematological and iron status at 4 respective 12 months of age in a large sample of full-term, Swedish infants.

The investigators also choose to investigate if the timing of clamping the umbilical cord could affect rate of infections during the first four months of life and to assess the infants development at 4 and 12 months of age.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01245296
Study type	Interventional
Source	Uppsala University
Contact
Status	Completed
Phase	N/A
Start date	April 2008
Completion date	May 2010

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01483768` - Study of Sleeve Gastrectomy on Iron Intestinal Absorption in Morbidly Obese Patients	N/A
Completed	`NCT02888171` - Impact of Ferric Citrate vs Ferrous Sulfate on Iron Parameters and Hemoglobin in Individuals With CKD and Iron Deficiency	N/A
Recruiting	`NCT02242188` - Supplementing Iron and Development in Breastfed Infants (SIDBI Study)	Phase 4
Completed	`NCT02714361` - A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women	N/A
Completed	`NCT02176759` - Iron Absorption From Rice Fortified With Ferric Pyrophosphate	N/A
Completed	`NCT01922479` - Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure	Phase 4
Completed	`NCT01991626` - Evaluation of the Effects of an Exogenous Phytase on Iron Absorption From LNS Added to Complementary Foods	N/A
Completed	`NCT01687062` - Iron Absorption From Tef-injera in Women of Reproductive Age	N/A
Completed	`NCT01573013` - Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children	N/A
Completed	`NCT01191463` - The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)	N/A
Completed	`NCT01443832` - Iron Absorption From Iron-fortified Fonio Porridge: a Stable Isotope Study	Phase 0
Completed	`NCT01061307` - An Efficacy Trial of Iron, Zinc and Vitamin A Fortified Rice in Children in Satun, Thailand	Phase 0
Not yet recruiting	`NCT00515918` - The Effect of Early Iron Deficiency on Developmental Brain and Behavior in Infants	N/A
Recruiting	`NCT00378469` - Study of the Effects of Muscular Activity on Iron Metabolism	N/A
Recruiting	`NCT05992116` - Iron Deficiency in Patients With Heart Failure and Reduced and Mildly Reduced Ejection Fraction
Completed	`NCT05262634` - Pregnancy Outcome in Women With an Iron Deficiency in the First Trimester
Completed	`NCT06080555` - Bioequivalence Study of Ferric Carboxymaltose Injection in Participants With Iron Deficiency Anaemia	Phase 1
Completed	`NCT04602247` - Evaluation of Iron Bioavailability From Iron Chlorophyllin	N/A
Completed	`NCT02996786` - Effects of Danggui Buxue Tang on Blood Biochemical Parameters in Male Recreational Runners	N/A
Completed	`NCT02175888` - The Optimization of Bioavailability From Iron Supplements: Study 1	N/A