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Evaluating the Effectiveness of Various Iron Salts and Carrier Systems in Oral Iron Therapy for Iron Deficiency and Anemia in Healthy Adults

Iron Deficiency Anemia Clinical Trial

Official title:
Evaluating the Effectiveness of Various Iron Salts and Carrier Systems in Oral Iron Therapy for Iron Deficiency and Anemia in Healthy Adults: A Randomized, Double-blind, Parallel-group Clinical Trial

Clinical Trial Summary

Oral iron supplements are a cornerstone therapy for treating iron deficiency and iron deficiency anemia, aiming to replenish low iron levels in the body. These supplements typically contain various iron salts, such as ferrous sulfate, ferrous gluconate, ferrous fumarate, ferric maltose and ferric pyrophosphate. Each salt differs in elemental iron content and potential side effects, allowing for tailored treatment based on individual patient needs and tolerability. Moreover, advancements in carrier systems, such as microencapsulation or complexation can enhance the absorption and bioavailability of iron supplements. By improving absorption, these carrier systems may mitigate gastrointestinal side effects and increase the efficacy of iron therapy.

Clinical Trial Description

The current randomized, parallel-group, clinical trial study aims to conduct a comparative analysis of the effectiveness of three different oral iron formulations: ferric maltose, ferric pyrophosphate, and sodium ferric pyrophosphate. Each of these formulations is delivered in a distinct carrier system. The study seeks to evaluate their efficacy in treating iron deficiency or iron deficiency anemia, two prevalent conditions associated with low iron levels in the body. By assessing various iron salts and carrier systems, the research aims to provide valuable insights into which formulation offers the most effective and well-tolerated treatment option for patients with iron deficiency or iron deficiency anemia. This comparative analysis may guide healthcare providers in selecting the most suitable oral iron supplement based on individual patient characteristics, ultimately optimizing treatment outcomes and improving patient care. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05985070
Study type Interventional
Source Liaquat University of Medical & Health Sciences
Contact
Status Recruiting
Phase N/A
Start date July 17, 2023
Completion date October 31, 2024
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