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Iron and Vaccine Response

Iron Deficiency Anemia Clinical Trial

Official title:
Iron and Vaccine-preventable Viral Disease - an Experimental Study

Clinical Trial Summary

Vaccines often underperform in Africa compared to high-income countries. Why vaccines do not work as well in Africa remains uncertain. Malnutrition likely plays a role. Our study objective is to assess whether iron deficiency anaemia in young women impairs their immune response to viral vaccines, and whether iron treatment improves their response.

Clinical Trial Description

Group 1 (immediate iron treatment) will receive iron treatment before vaccination. Women in both groups will receive two intramuscular vaccines (influenza and yellow fever). Vaccine response will be measured 28 and 56 days after vaccine administration in both groups. Group 2 (delayed iron treatment) will receive iron treatment at study end. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04912661
Study type Interventional
Source Swiss Federal Institute of Technology
Contact
Status Completed
Phase N/A
Start date May 29, 2021
Completion date September 9, 2021
View Details
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