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Iron Deficiency Anemia clinical trials

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NCT ID: NCT03933813 Terminated - Anemia Clinical Trials

Evaluation and Treatment of Iron Deficiency in Ovarian Cancer Patients

Start date: July 29, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study tests the hypothesis that IV iron sucrose infusions given to iron deficient ovarian cancer patients prior to debulking surgery can improve pre-operative iron stores and decrease transfusion of packed red blood cells in the peri-operative period. 21 participants at least 18 years of age with epithelial ovarian cancer of any stage requiring neoadjuvant chemotherapy and surgery will be enrolled. Participants will be on study for a period of up to 3 months.

NCT ID: NCT03485053 Terminated - Clinical trials for Iron Deficiency Anemia

A Single Ascending Study of IOP Injection in Patients With Iron Deficient Anemia

Start date: November 29, 2018
Phase: Phase 2
Study type: Interventional

The purpose is to evaluate the efficacy and safety of IOP Injection (MPB-1514) for the treatment of iron-deficient anemia (IDA).

NCT ID: NCT02973074 Terminated - Clinical trials for Iron Deficiency Anemia

Oral Iron Substitution for Orthopedic Surgery

Start date: November 25, 2016
Phase: N/A
Study type: Interventional

The aim of this pilot study is to investigate an 4 weeks period of oral iron substitution in the course of Patient Blood Management in preparation for orthopedic surgery.

NCT ID: NCT02518568 Terminated - Clinical trials for Iron Deficiency Anemia

Ferrous Sulphate Supplement (V0355) in Women With Iron Deficiency Anaemia

Start date: August 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the pharmacokinetics of serum iron after a single oral administration of 160 mg (2 tablets of 80 mg) V0355 in women with iron deficiency anaemia.

NCT ID: NCT02341300 Terminated - Clinical trials for Iron-deficiency Anemia

Use of Cast Iron Pots to Improve Maternal Anemia

Start date: July 15, 2020
Phase: N/A
Study type: Interventional

Anemia of pregnancy is defined as a hemoglobin concentration of less than 11 g/dL in the first and third trimesters, and less than 10.5 g/dL in the second trimester. The rates of anemia are variable and depend largely on preexisting iron stores and supplementation. Estimates from the World Health Organization report that 35% to 75% of pregnant women in developing countries and 18% of women from industrialized countries are anemic. Maternal anemia is associated with an increased risk of preterm birth, low birthweight, and small for gestational age infants. Many studies have shown improvement in these outcomes with maternal iron supplementation in cases of iron-deficiency anemia. Mounting evidence also indicates that maternal iron deficiency in pregnancy reduces fetal iron stores, perhaps well into the first year of life. Anemia in pregnancy can also impact maternal morbidity and mortality. Viteri reported that anemic pregnant women are at greater risk of death during the perinatal period and that anemia is the major contributory or sole cause of death in 20-40% of the 500,000 maternal deaths per year. The need for iron averages close to 1000mg in a typical singleton gestation. This amount considerably exceeds the iron stores of most women and will result in iron-deficiency anemia unless supplemental iron is taken. One problem with iron supplement use is compliance, secondary to adverse effects such as constipation and nausea. Research on the use of cast iron pots in decreasing the incidence of iron-deficiency anemia in non-pregnant women has been promising. These studies have demonstrated good compliance with no reported adverse effects. The aim of our study is to determine if providing anemic women in the first trimester of pregnancy with a cast iron pot will decrease the incidence of anemia later in pregnancy. Hypothesis: Cooking in cast iron pots will increase hematocrit levels in pregnancy.

NCT ID: NCT01264679 Terminated - Clinical trials for Iron Deficiency Anemia

A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease

Start date: December 27, 2011
Phase: Phase 3
Study type: Interventional

Study AMAG-FER-CKD-253 is an extension study of the combined AMAG-FER-CKD-251 (NCT01155375) and AMAG-FER-CKD-252 (NCT01155388) studies to evaluate the efficacy and safety of episodic treatment of iron deficiency anemia (IDA) with ferumoxytol.

NCT ID: NCT01155388 Terminated - Clinical trials for Iron Deficiency Anemia

A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Nondialysis-Dependent Chronic Kidney Disease

Start date: October 17, 2011
Phase: Phase 3
Study type: Interventional

Study evaluating the efficacy and safety of intravenous (IV) ferumoxytol compared with oral iron for the treatment of pediatric participants with chronic kidney disease (CKD).

NCT ID: NCT01155375 Terminated - Clinical trials for Iron Deficiency Anemia

A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease

Start date: October 17, 2011
Phase: Phase 3
Study type: Interventional

Study evaluating the efficacy and safety of intravenous (IV) ferumoxytol compared with oral iron for the treatment of pediatric participants with chronic kidney disease (CKD).

NCT ID: NCT01100879 Terminated - Clinical trials for Iron-Deficiency Anemia

Ferric Carboxymaltose for Treatment of Anaemia of Cancer in Subjects With Multiple Myeloma Receiving Chemotherapy

AOC-MM
Start date: March 2010
Phase: Phase 4
Study type: Interventional

Multicentre, randomised, controlled, 2-arm open-label prospective pilot study to evaluate efficacy and safety of ferric carboxymaltose (FCM) in treatment of anaemia in subjects with multiple myeloma (MM) initiating chemotherapy. The subjects will be screened for eligibility within 4 weeks prior to inclusion and randomised to receive intravenous infusions of FCM or standard care (the subjects may be treated according to the local institutional practice if requiring symptomatic management of anaemia). Thereafter the visits are scheduled at Weeks 0, 2, 4, 6 and 8.

NCT ID: NCT00882414 Terminated - Clinical trials for Iron-Deficiency Anemia

Ferinject® in Patient With Thrombocytosis Secondary to Inflammatory Bowel Disease (IBD)

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The aim of this study is to show the benefits for patients, with a high platelet count, iron deficiency and IBD, receiving intravenous iron therapy.