Iron Absorption Trial

Status Completed

Clinical Trial Summary

Introduction: There are indications that the absorption of oral iron supplementation is reduced after a Roux- en -Y gastric bypass. Nevertheless, oral preparations are used as standard therapy for iron deficiency, even in patients who underwent a Roux- en -Y gastric bypass. Our goal is to evaluate if iron absorption is disturbed after a RYGB, which leads to a insufficient treatment of oral iron suppletion.

Methods: an iron absorption test will be performed pre- and postoperatively in 24 patients. Two groups will be created.

Preoperatively group 1 receives a daily dose of ferrous fumarate (600mg) and group 2 receives a daily dose Losferron (1390mg).

Before intake of the medicines, a fasting blood sample is taken (baseline), serum iron including ferritin, transferrin and transferrin saturation will be measured. After intake of losferron/ferrous fumarate blood samples will be taken 1, 2, 3, 4, 5 and 6 hours after intake, using a drip. An increase of 80 microgram/l is representative for a sufficient iron absorption. All patients undergo a Roux- en -Y gastric bypass.

Postoperatively; one month postoperatively the same absorption test will be repeated in the same patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02228902
Study type	Interventional
Source	Rijnstate Hospital
Contact
Status	Completed
Phase	Phase 4
Start date	August 2014
Completion date	May 4, 2015

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT04517591` - Reducing Sedentary Time in Bariatric: The Take a STAND for Health Study	N/A
Active, not recruiting	`NCT04433338` - The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery	N/A
Completed	`NCT05854875` - Diabetes Remission After RYGBP and RYGBP With Fundus Resection	N/A
Recruiting	`NCT06460233` - Blood Pressure Changes After Bariatric Surgery
Completed	`NCT00535600` - Effects of Bariatric Surgery on Insulin
Withdrawn	`NCT04771247` - Endoscopic Cardiac Band Ligation for the Management of Refractory GERD After Laparoscopic Sleeve Gastrectomy	N/A
Not yet recruiting	`NCT03203161` - Registry on Obesity Surgery in Adolescents
Enrolling by invitation	`NCT02552433` - Complications in Body Contouring Surgery
Completed	`NCT02525016` - Safety Profile of IntRAvenous Lidocaine Use in Coelioscopic Bariatric Surgery	Phase 3
Recruiting	`NCT01984762` - Sleeve Gastrectomy and Roux-en-Y Gastric Bypass in the Treatment of Type 2 Diabetes Mellitus.	N/A
Not yet recruiting	`NCT01652105` - Randomized Trial of Preoperative Diets Before Bariatric Surgery	N/A
Completed	`NCT00989157` - Effects of Gastric Bypass on Blood Levels of Duloxetine	Phase 3
Completed	`NCT03609632` - Understanding Hypoglycaemia After Bariatric Surgery	N/A
Completed	`NCT05454696` - Online Clinic Pilates Exercises in Patients Undergoing Bariatric Surgery	N/A
Completed	`NCT04040647` - Tolerance of Early Postoperative Mobilization and Ambulation
Recruiting	`NCT04297306` - Virtual Reality Exercise Gaming in Patients Awaiting Bariatric Surgery	N/A
Recruiting	`NCT05428618` - Mobile Application for Bariatric Surgery Patients	N/A
Not yet recruiting	`NCT03900481` - Use of an Endoluminal-suturing Device for Endoscopic Gastric Reduction as an Aid for Class I Obesity, or Class II Obesity Without Comorbidity	N/A
Not yet recruiting	`NCT03975244` - Semi-supervised Exercise Program Before Bariatric Surgery	N/A
Recruiting	`NCT06170749` - Prediction Model for Anemia After Bariatric Surgery