IPEX Clinical Trial - Immune Disorder HSCT Protocol

Status Recruiting

Clinical Trial Summary

This study hypothesizes that a reduced intensity immunosuppressive preparative regimen will establish engraftment of donor hematopoietic cells with acceptable early and delayed toxicity in patients with immune function disorders. A regimen that maximizes host immune suppression is expected to reduce graft rejection and optimize donor cell engraftment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Agammaglobulinemia
Autoimmune Lymphoproliferative Syndrome
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Common Variable Immune Deficiency
Common Variable Immunodeficiency
DiGeorge Syndrome
Granulomatous Disease, Chronic
Hemophagocytic Lymphohistiocytosis
Hyper-IgM
Immune Deficiency Disorders
Immune Dysregulatory Disorders
Immunologic Deficiency Syndromes
IPEX
Lymphohistiocytosis, Hemophagocytic
Lymphoproliferative Disorders
Severe Combined Immunodeficiency
Syndrome
Wiskott-Aldrich Syndrome
X-linked Agammaglobulinemia
X-linked Lymphoproliferative Syndrome

Clinical Trial Details

NCT number	NCT01821781
Study type	Interventional
Source	Washington University School of Medicine
Contact
Status	Recruiting
Phase	Phase 2
Start date	March 2013
Completion date	March 2027

View Details

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