Invasive Ventilatory Support Clinical Trial
Official title:
NAVADYN11 : Hemodynamic Impact of a New Ventilatory Support Mode With Diaphragmatic Synchronization
Despite spectacular advances since the 90s mechanical ventilation used in intensive care
units are amply associated with cardio-respiratory complications: nosocomial pneumonia, lung
parenchyma lesions induced by ventilation, hemodynamic instability and ultimately to a
significant morbidity and mortality.
NAVA (Neurally Adjusted Assist Ventilation) ventilatory support, provides synchronous
support, proportionate to patient's respiratory efforts. More "physiological", this mode
would decline its efficacy on patient hemodynamic response. However, to date, no study has
focused on hemodynamic impact of NAVA. This is precisely the purpose of NAVADYN11 study,
which aims to assess NAVA efficacy on cardiac index in pediatric intensive care unit.
n/a
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Health Services Research