Invasive Pneumococcic Clinical Trial
Official title:
Identification and Quantification of Immune Response Induced by Hyaluronidase and Other Factors of Virulence of Invasive Human Infections of Streptococcus Pneumoniae
- 4 tubes (2 x7-ml dry tubes with yellow gelose, and 2 x 5 ml tubes with blue CTAD) will
be taken from the patient within 24 hours following inclusion (D0) in the department in
which the patient is hospitalised
- 4 tubes (2 x7-ml dry tubes with yellow gelose, and 2 x 5 ml tubes with blue CTAD) will
be taken from the patient every 7 days following inclusion for 5 weeks (if the patient
is still in hospital at the time), in the department where he/she is hospitalised (D7,
D14, D21, D28, D35). Samples will no longer be taken once the patient has left the CHU,
even if all of the samples have not been taken.
- For children less than 6 years old, only 2 tubes (1 x 7 ml dry tube with yellow gelose,
and 1x5 ml tube with blue CTAD) will be taken following the same timetable.
- For hospitalised patients, a leeway of 48 hours is authorized for the sampling
procedure. Samples will be taken at the same time samples are taken for the usual care
of the patient.
- The tubes will be taken to the Bacteriology Laboratory using the usual collection
circuit of the CHU. These tubes will then be redirected to the Infectious Diseases
Laboratory to be centrifuged and then stored at -80°C. The strain of Streptococcus
pneumoniae isolated in the patient will be preserved at -80°C. If strains other than
Streptococcus pneumoniae are isolated, these different strains will all be preserved at
-80°C under the same identification number.
n/a