Invasive Mechanical Ventilation Clinical Trial
Official title:
Safety and Efficacy of Fospropofol vs Propofol During Invasive Mechanical Ventilation in Anesthesiology Intensive Care Unit: A Preliminary Study
The goal of this clinical trial is to compare the safety and efficacy of fospropofol and propofol during sedation in invasively mechanically ventilated patients in the Anesthesia Intensive Care Unit (AICU). Specific objectives include the following: - Evaluate the sedative effects of fospropofol and propofol in invasively mechanically ventilated patients. Compare the sedative effects of the two medications using relevant clinical indicators and scoring tools, such as the Richmond Agitation-Sedation Scale (RASS). - Compare the safety of fospropofol and propofol during sedation. Monitor medication-related adverse reactions, such as respiratory depression, hypotension, arrhythmias, headache, injection site pain, and assess the differences in adverse reaction incidence between the two medications. - Compare the characteristics of recovery from sedation between PPD and propofol. Focus on the time from sedation to emergence from sedation and compare the differences in recovery time between the two medications. Participants will be sedated with fospropofol or propofol during invasive mechanical ventilation.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02877524 -
Trial to Study Intubation Rates of Non-invasive Ventilation Using Pressure Support Ventilation (PSV) Versus Adaptive Support Ventilation (ASV) Mode in Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
N/A | |
| Completed |
NCT04199273 -
Assessment of Human Diaphragm Strength by Magnetic and Electric Stimulation After Ultrasonography Phrenic Nerve Tracking
|
N/A | |
| Completed |
NCT03955874 -
Mechanical Ventilation Discontinuation Practices
|
||
| Not yet recruiting |
NCT06288724 -
MOdifiable facTors to Improve VentilAtion ThErapy in ICU
|
||
| Not yet recruiting |
NCT06217406 -
Preemptive Treatment With Acyclovir in Intubated and Mechanically Ventilated Patients With Herpes (PTH2)
|
N/A | |
| Terminated |
NCT03460015 -
Sevoflurane in Chronic Obstructive Pulmonary Disease Exacerbation
|
N/A | |
| Completed |
NCT04383730 -
Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19)
|
||
| Recruiting |
NCT05056961 -
Effects of Large Tidal Volumes Despite Minimal Inspiratory Support in Spontaneously Ventilated Intubated Resuscitation Patients. Pathophysiological Exploratory Study.
|
N/A | |
| Completed |
NCT02380547 -
Sonographic Evaluation of Diaphragmatic Function in Critical Care Patients With Use of Non Invasive Ventilation
|
||
| Terminated |
NCT04222569 -
Determination of the Optimal Spontaneous Breathing Trial During Weaning of Mechanical Ventilation
|
N/A | |
| Recruiting |
NCT05880953 -
Parent-to-parent Coaching While Awaiting Hospital Discharge With a Child With a Ventilator
|
N/A | |
| Withdrawn |
NCT02617914 -
Hemodynamic and Cardiac Effects of Individualized PEEP Titration Using Esophageal Pressure Measurements in ARDS Patients
|
N/A | |
| Recruiting |
NCT05668637 -
Evaluation and Further Development of an Artificial Intelligence-based Algorithm for Clinical Decision Support
|
||
| Completed |
NCT02877498 -
A Study to Compare Adaptive Support Ventilation vs. Volume Controlled Ventilation for Management of Respiratory Failure in Patients With Neuroparalytic Snake Envenomation
|
N/A | |
| Recruiting |
NCT05081973 -
A Model for Predicting Extubation Success in Premature Babies
|