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Intussusception clinical trials

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NCT ID: NCT02542462 Completed - Clinical trials for Rotavirus Infections

Potential Mechanisms for Intussusception After Rotavirus Vaccine-Pilot Study

Start date: November 2015
Phase: Phase 4
Study type: Interventional

This is a prospective randomized clinical trial that aims to evaluate the potential effects of the first dose of rotavirus vaccines on gastrointestinal motility and anatomy and blood and stool cytokine responses. It will also assess the association between these outcomes and the pattern of the shedding of vaccine strain rotavirus in the stool. Infants will be randomized to one of four arms: monovalent rotavirus vaccine (Rotarix®, RV1) alone, RV1 with other recommended vaccines, pentavalent rotavirus vaccine (RotaTeq®, RV5) alone, or RV5 with other recommended vaccines. Data derived from the pilot study will be used to assess the feasibility of conducting a larger scale study.

NCT ID: NCT01479491 Completed - Intussusception Clinical Trials

Study on the Incidence of Intussusception (IS) in Children Aged < 12 Months in Japan

Start date: November 2011
Phase: N/A
Study type: Observational

This study aims to analyse baseline data on IS in order to monitor the possibility of increased risk of IS in children aged <12 months after introduction of the Rotarix vaccination in Japan.

NCT ID: NCT01177839 Completed - Intussusception Clinical Trials

Study to Assess the Incidence of Intussusception in Children < 2 Years of Age in Singapore

Start date: May 2002
Phase: N/A
Study type: Observational

This prospective study aims to estimate the incidence of intussusception among children < 2 years old through hospital-based surveillance in Singapore.

NCT ID: NCT00673400 Completed - Rectocele Clinical Trials

Stapled TransAnal Rectal Resection (STARR) With Contour® TranstarTM

STARR
Start date: January 2008
Phase: N/A
Study type: Interventional

The stapled transanal rectal resection (STARR procedure) is an effective treatment for obstructed defecation syndrome (ODS) caused by intussusception and rectocele. Recently a new technique has been developed using the new Contour® TranstarTM stapler, which was specifically designed to facilitate the STARR procedure. The investigators would like to evaluate the morbidity and quality of life.

NCT ID: NCT00595205 Completed - Rotavirus Vaccines Clinical Trials

Intussusception Surveillance After Rotarix Introduction in Mexico

Start date: January 2008
Phase: N/A
Study type: Observational

GSK Biologicals' rotavirus vaccine, Rotarix™ has been recommended for universal use targeting infants through the Expanded Program on Immunization (EPI) in Mexico. This protocol describes a Phase IV safety study in Mexico designed to further evaluate the safety profile of Rotarix™ with regard to intussusception (IS). The data generated by this study will be useful for public health officers and policy makers in confirming the safety profile of Rotarix™.

NCT ID: NCT00556283 Completed - Rectocele Clinical Trials

RCT: STARR vs Biofeedback

ODS II
Start date: February 2004
Phase: Phase 4
Study type: Interventional

This study aimed to evaluate the safety and symptomatic outcomes achieved with Stapled Transanal Rectal Resection (STARR) compared to biofeedback training in patients with obstructed defecation syndrome (ODS).

NCT ID: NCT00436358 Completed - Intussusception Clinical Trials

Implementing Hospital-based Active Surveillance Procedures for Vaccine Safety Monitoring at IMSS Hospitals in Mexico

Start date: April 2007
Phase: N/A
Study type: Observational

This is an epidemiology study designed to implement hospital-based active surveillance for intussusception (IS) in children <1 year of age and lower respiratory tract infection (LRTI)-related deaths among children between 29 days and 1 year of age in Mexico. An existing linked database of the "Instituto Mexicano del Seguro Social (IMSS)" will be used. The study described in this protocol is a pilot study, which will evaluate the methodology to be used in a later Post-Marketing Surveillance (PMS) study. The planned epidemiology study will be conducted in IMSS hospitals and potentially use the IMSS database to re-capture potential cases of IS and fatal cases and as a source of matched case controls. The purpose of this project is to complement this data link system with an active surveillance system for IS - in order to assess the feasibility of using the IMSS data system by generating results that provide scientific validity. Such comprehensive (passive and active) surveillance systems will facilitate the post licensure safety profile evaluation of vaccines such as a vaccine against rotavirus diarrhoea. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

NCT ID: NCT00256984 Completed - Clinical trials for Chronic Constipation

Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS)

Start date: October 1, 2005
Phase: Phase 4
Study type: Interventional

The primary purpose of this study is to determine how effective and how durable STARR (stapled transanal rectal resection) surgery is in relieving symptoms of intractable constipation associated with obstructive defecation syndrome (ODS).