Utah Study Evaluating Apneic Oxygenation for Emergency Department Intubation

Intubation Clinical Trial

— USE AP OX  

Official title:

Utah Study Evaluating Apneic Oxygenation for Emergency Department Intubation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02961933
• Other study ID #: 1050200
• Status: Recruiting
• Phase: N/A
• Start date: December 2016
• Est. completion date: June 2020

Study information

• Verified date: February 2020
• Source: Intermountain Health Care, Inc.
• Contact: Valerie Aston, MBA, RT
• Phone: 801-507-4606
• Email: valerie.aston[@]imail.org
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will determine rates of first pass success without hypoxemia in emergency department intubations with and without the use of apneic oxygenation by nasal cannula.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 500
• Est. completion date: June 2020
• Est. primary completion date: January 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients requiring emergent Rapid Sequence or Delayed Sequence endotracheal intubation with administration of a neuromuscular blocker (Succinylcholine, Rocuronium)

Exclusion Criteria:

• Known prisoners

• Patients in cardiac arrest

• Patients who are intubated without the use of neuromuscular blockade (i.e., cardiac arrest, awake intubation).

Related Conditions & MeSH terms

• Emergencies
• Intubation

Intervention

Other:
• Apneic oxygenation
Nasal cannula apneic oxygenation
• Pre-oxgenation with NRB, NIPPV, BVM
Pre-oxygenation with non-rebreather mask, non-invasive positive pressure ventilation, or bag-valve mask

Locations

Country	Name	City	State
United States	Intermountain Medical Center	Murray	Utah

Sponsors (2)

Lead Sponsor	Collaborator
Intermountain Health Care, Inc.	University of Utah

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	First pass success without hypoxemia		10 minutes
Secondary	Change in peri-intubation saturation		0, 30, 60 and 120 seconds
Secondary	Saturation at time of tube placement		10 minutes
Secondary	Time to desaturation <93%		measured time until saturations drop below 93% during the peri-intubation period, up to 10 minutes
Secondary	Saturation at post intubation		0, 30, 60, and 120 seconds