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NCT00783731 Clinical Trial

Low Dose of Midazolam is Superior to Conventional Dose for Rapid Sequence Intubation in Emergency Department (ED)

Intubation Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00783731
Other study ID # RSI study
Secondary ID
Status Completed
Phase N/A
First received October 30, 2008
Last updated July 25, 2011
Start date October 2008
Est. completion date January 2011

Study information
Verified date July 2011
Source Seoul National University Hospital
Contact n/a
Is FDA regulated No
Health authority Korea: Food and Drug Administration
Study type Interventional

Clinical Trial Summary

Midazolam has been used in rapid sequence intubation for a long time, and the recommended dose is 0.1mg/kg. In some studies, however, the reduced dose has been used with the concern of hemodynamic instability. We would like to investigate that the low dose midazolam could be used rather than the standard recommended dose, and also compare it to the etomidate, recently used sedatives, with respect to the side effects and the easy performance of intubation.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date January 2011
Est. primary completion date October 2010
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- patients who need rapid sequence intubation in emergency room

Exclusion Criteria:

- in hypotension(systolic blood pressure less than 90 mmHg

- severe trauma patients

- pregnant

- allergic to midazolam, etomidate

Study Design

Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Low dose midazolam

Locations
Country Name City State
Korea, Republic of Seoul National University Bundang Hospital, Emergency room Seongnam-si Gyeonggi-do
Korea, Republic of Boramae Medical Center Seoul

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

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