Clinical Trials Logo

Intrusive Memories clinical trials

View clinical trials related to Intrusive Memories.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT05678361 Completed - PTSD Clinical Trials

Sleep's Influence on the Treatment of Intrusive Emotional

SLEPT
Start date: August 1, 2018
Phase: N/A
Study type: Interventional

Intrusive memories represent a debilitating core feature of PTSD, one of the most prevalent psychiatric disorders following trauma. Exposure therapy is amongst the most successful treatments of PTSD that is recommended by most of the current national and international guidelines. The current study aims to test whether sleep as adjunct to written exposure sessions, a type of exposure- based treatment for PTSD, may boost the effectiveness of the therapy.

NCT ID: NCT05063825 Completed - Intrusive Memories Clinical Trials

Understanding Reactions to Emotional Material in the Media During COVID-19 - Study 2

Start date: October 6, 2021
Phase: N/A
Study type: Interventional

This second feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task intervention) to remote (online) delivery. The motivation for this was restrictions to running in person laboratory experiments during the COVID-19 pandemic. Non-clinical participants will view film footage with COVID-19 related and potentially traumatic content (e.g. of seriously ill or dying patients in hospitals). Following film viewing, participants will be randomly allocated to either the experimental condition (simple cognitive task intervention, i.e. a memory cue followed by playing the computer game "Tetris" with mental rotation instructions) or the control condition (attention placebo, i.e., a memory cue followed by listening to a podcast for a similar duration). Any intrusive memories induced by the film (analogue trauma) will be monitored in a daily diary. It is predicted that the film (analogue trauma) will generate intrusive memories. If intrusive memories are generated, then it is predicted that participants in the experimental condition will report fewer intrusive memories related to the film (analogue trauma) during the following week than participants in the control condition. The development of this paradigm may inform the future development of a simple technique to prevent intrusive memories e.g. after repeated media consumption related to the COVID-19 pandemic.

NCT ID: NCT04608097 Completed - Clinical trials for Healthy Participants

Understanding Reactions to Emotional Material in the Media During COVID-19

Start date: October 28, 2020
Phase: N/A
Study type: Interventional

This feasibility study aims to adapt a protocol usually run in the laboratory in the Psychology Department for healthy participants (including the trauma film paradigm (James et al., 2016) and a simple cognitive task intervention) to remote (online) delivery. The motivation for this was restrictions to running in person laboratory experiments during the COVID-19 pandemic. Participants will view film footage with COVID-19 related and potentially traumatic content (e.g. of seriously ill or dying patients in hospitals). Following film viewing, participants will be randomly allocated to either the experimental condition (simple cognitive task intervention, i.e. a memory cue followed by playing the computer game "Tetris" with mental rotation instructions) or the control condition (attention placebo, i.e., a memory cue followed by listening to a podcast for a similar duration). Any intrusive memories induced by the film (analogue trauma) will be monitored in a daily diary. It is predicted that the film (analogue trauma) will generate intrusive memories. If intrusive memories are generated, then it is predicted that participants in the experimental condition will report fewer intrusive memories related to the film (analogue trauma) during the following week than participants in the control condition. The development of this paradigm may inform the future development of a simple technique to prevent intrusive memories e.g. after repeated media consumption related to the COVID-19 pandemic.

NCT ID: NCT03875391 Completed - PTSD Clinical Trials

The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories

Start date: March 6, 2019
Phase: N/A
Study type: Interventional

The purpose of the study is to examine whether oxytocin and certain polygenic risk scores affect the development of intrusive memories, a cardinal symptom of PTSD.

NCT ID: NCT03227081 Completed - Intrusive Memories Clinical Trials

Behavioral Modulation of Intrusive Memories

Start date: July 17, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to examine whether sleep affects the development of intrusive memories.

NCT ID: NCT03031405 Completed - Intrusive Memories Clinical Trials

The Effect of Oxytocin on the Acquisition and Consolidation of Trauma-Associated Memories

Start date: January 15, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to examine whether oxytocin and oxytocin receptor gene polymorphism affect the development of intrusive memories, a cardinal symptom of PTSD.

NCT ID: NCT03012685 Completed - Sleep Clinical Trials

Sleep and Wellbeing Study

Start date: November 2016
Phase:
Study type: Observational

Most people will experience a psychologically traumatic event, such as a life-threatening accident, at some point in their life. In the initial days after such an event, it is common to be haunted by intrusive memories: image-based memories of the event that spring to mind unbidden. Intrusive memories can be distressing in their own right, but are also a hallmark symptom of post-traumatic stress disorder (PTSD). Sleep is important for many functions involved in how people perceive, respond to and remember events, including stressful/traumatic events. Studies with patients who have experienced traumatic events indicate that sleep disturbances in the first weeks post-trauma are associated with later PTSD symptoms. However, in a previous study with healthy volunteers exposed to experimental trauma (film footage), those who were sleep-deprived in the first night, compared to those who slept, had fewer intrusive memories in the following week. This raises the question of how sleep in the first night, but also the first week, after real-life trauma is related to subsequent intrusive memories and PTSD symptoms. The current study is an observational study of patients recruited from a hospital emergency department after a traumatic event. After completing brief baseline questionnaires in the emergency department, participants will be asked to fill in a daily diary of their sleep and intrusive memories over the following week. Post-traumatic stress symptoms, anxiety and depression will be assessed by post/online at one week and two months. Participants will be telephoned after two months to complete an interview to assess PTSD symptoms and an optional feedback interview. This clinical study will be the first to assess the relationship between sleep in the first night and week, and intrusive memories and mental wellbeing after real-life trauma. Findings may have implications for developing simple sleep-based preventive treatments after trauma in the future.

NCT ID: NCT02552654 Completed - Intrusive Memories Clinical Trials

Cortisol and the Formation of Intrusive Memories

Start date: September 2015
Phase: N/A
Study type: Interventional

Intrusive memories of traumatic events are core features of posttraumatic stress disorder (PTSD) but little is known about the neurobiological formation of intrusions. The aim of this study was to determine whether cortisol levels during an intrusion-inducing stressor influence subsequent intrusive memories.

NCT ID: NCT02541071 Completed - Intrusive Memories Clinical Trials

Influence of the Noradrenergic System on the Formation of Intrusive Memories

Start date: November 2013
Phase: N/A
Study type: Interventional

Intrusive memories of traumatic events are core features of posttraumatic stress disorder (PTSD) but little is known about the neurobiological formation of intrusions. The aim of this study was to determine whether the activity of the noradrenergic system during an intrusion-inducing stressor influences subsequent intrusive memories.