Diabetic Macular Edema Clinical Trial
Official title:
The Effect of Dexamethasone Implant on Retinal Nerve Fiber and Optic Disc Morphology in Patients With Diabetic Maculopathy
This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measured before and 6 months after the injection.
Diabetic macular edema is the most frequent ocular complication of diabetes resulting in
irreversible loss of vision if untreated. Dexamethasone implant implant is used to treat
macular edema due to diabetes. It stay in the vitreous for 6 months after intravitreal
administration.
Dexamethasone implant can lead to retinal nerve fiber layer and optic nerve damage by both
increasing intraocular pressure and its direct effect on neural tissue during the effective
6-month period.
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