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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03808571
Other study ID # 1
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2018
Est. completion date January 15, 2019

Study information

Verified date January 2019
Source Yuzuncu Yil University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

: The aim of this study is to investigate Cord blood irisin and nesfatin-1 levels in pregnancies with intrauterine growth retardation and to determine whether they are associated with abnormal fetal doppler findings or not.


Description:

This study was conducted at Yüzüncü Yıl University Medical Faculty Obstetrics and Gynecology Clinic. The study group included 34 pregnant women ranged from 18 to 45 years old who have intrauterine growth retardation and underwent ceseraen section. 32 pregnant women who had no abnormality on prenatal follow-up and underwent elective ceserean seciton served as control group. The maternal age, height, weight, body mass index (BMI), systolic and diastolic blood pressures were recorded in both groups of patients. Maternal serum total blood count and biochemical parameters were obtained from the laboratory parameters. Gestational week at birth, birth weight, sex, 1st and 5th minute APGAR scores were recorded. Blood samples were collected from all the cases during the cesarean section for measurmenet of nesfatin-1 and irisin by doubly clamped umbilical cord. Blood samples were immediately centrifuged in sterile tubes and maintained at -80 ° C until assessed.


Recruitment information / eligibility

Status Completed
Enrollment 66
Est. completion date January 15, 2019
Est. primary completion date January 10, 2019
Accepts healthy volunteers
Gender Female
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria:

- Pregnant women with intrauterine grwoth rectricted fetuses.

- Healthy pregnancies

Exclusion Criteria:

- Pregnant women with chronic medical conditions

- multiple pregnancies

- fetuses with fetal malfomations or genetic syndromes

- pregnant women older than 45 years old

Study Design


Intervention

Other:
cord blood specimen during the delivery
The cord blood will be taken during the delivery of baby.

Locations

Country Name City State
Turkey Yuzuncu Yil University, Medical faculty, department of obstetric and gynecology Van

Sponsors (1)

Lead Sponsor Collaborator
Yuzuncu Yil University

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary cord blood nesfatn-1 level measurement cord blood levels of nesfatin-1 in pregnancies with intrauterine growth restricted fetuses and healthy pregnancies. 9 months
Secondary Cord blood irisin level measurement ord blood levels of irisin in pregnancies with intrauterine growth restricted fetuses and healthy pregnancies. 9 months
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