Intrauterine Growth Restriction Clinical Trial
Official title:
Intrauterine Growth Restriction Has an Impact on Amplitude-integrated EEG in Preterm Infants
Objective: The impact of intrauterine growth restriction (IUGR) on perinatal morbidity and
long-term neurodevelopmental outcome has been published in numerous studies. Throughout this
analysis, the influence of IUGR on the postnatal amplitude-integrated EEG (aEEG) in preterm
infants below 30 weeks of gestation was assessed. The second concern was the correlation
between the pattern of the aEEG in the first two weeks with neurodevelopmental outcome,
comparing infants with and without IUGR.
Methods: Routinely assessed aEEG data of preterm infants with IUGR born below 30 weeks of
gestation in the years 2005 until 2007 were analysed retrospectively according to the aEEG
score (combining occurrence of sleep-wake-cycles, background activity and suspected seizure
activity). Neurodevelopmental outcome was evaluated at 24 months using the Bayley Scales of
Infant Development and standardized neurologic examination.
n/a
Observational Model: Cohort, Time Perspective: Retrospective
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