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The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis

Intrauterine Adhesion Clinical Trial

Official title:
The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis

Clinical Trial Summary

The purpose of this study is to investigate the efficacy of Granulocyte Colony Stimulating Factor(G-CSF) on decreasing adhesion reformation and improving fertility outcomes after hysteroscopic adhesiolysis in patients with moderate to severe intrauterine adhesions.

Clinical Trial Description

After hysteroscopic adhesiolysis, patients with moderate to severe intrauterine adhesions will be allocated into 2 groups randomly, with COOK ballon and estrogen and progesterone sequential therapy given to prevent adhesion routinely. 7 day later, G-CSF or normal saline will be injected into the uterine cavity by Tom catheter after removing the balloon respectively. A second hysteroscopic examination will be performed in 2 months to check up the adhesion reformation. In addition, the endometrial thickness after surgery and fertility outcome will be followed up. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02855632
Study type Interventional
Source Sir Run Run Shaw Hospital
Contact Xiaona Lin, Doctor
Phone +8657186006252
Email linna73@263.net
Status Recruiting
Phase N/A
Start date August 2016
Completion date December 2019
View Details
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