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Intrauterine Adhesion clinical trials

View clinical trials related to Intrauterine Adhesion.

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NCT ID: NCT04936347 Recruiting - Clinical trials for Intrauterine Adhesion

Hysteroscopic "Hot Knife" and "Cold Knife" in the Treatment of the Intrauterine Adhesion

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

In this prospective, randomized controlled trial,the investigators wish to explore the difference of therapeutic effect and prognosis between "hot knife" and "cold knife" in the treatment of uterine adhesion under hysteroscopy.

NCT ID: NCT04930913 Recruiting - Clinical trials for Intrauterine Adhesion

Three-dimensional Ultrasound Applying in Assessment of Intrauterine Adhesions

Start date: July 1, 2020
Phase:
Study type: Observational

In this prospective, multicenter, large-scale study,the investigators wish to examine the accuracy of several three-dimensional ultrasound anatomical and vascular parameters in diagnosing IUA when compared to the gold standard of hysteroscopy,and to assess the value of 3D US applying in prognosis of intrauterine adhesions.

NCT ID: NCT04824430 Completed - Clinical trials for Intrauterine Adhesion

Assessment of Uterine Access, Uterine Patency and Intrauterine Adhesions Following Endometrial Ablation

Start date: March 23, 2021
Phase:
Study type: Observational

The objective of this study is to gain information concerning the acute and longer-term morphological changes within the uterus following endometrial ablation. Hysteroscopic evaluation of the uterine cavity will be used to determine if physical access and the ability to systematically assess the post-ablation uterine cavity were preserved. The presence, location and severity of intrauterine adhesions will be documented in participants who are 3, 6 and 12 months from their standard of care endometrial ablation.

NCT ID: NCT04705324 Recruiting - Clinical trials for Intrauterine Adhesion

Dilation and Curettage Versus Operative Hysteroscopy for Missed Abortion

Start date: January 21, 2022
Phase: N/A
Study type: Interventional

Randomizedtrial comparing success and complication rates of operative hysteroscopy versus traditional dilation and curettage (D&C) in the management of first trimester missed abortion.

NCT ID: NCT04637373 Recruiting - Clinical trials for Intrauterine Adhesion

Hysteroscopy Assisted Suction Curettage for Early Pregnancy Loss

Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Retained products of conception (RPOC) and intrauterine adhesions (IUA) may occur following suction curettage for early miscarriage and cause secondary infertility, recurrent pregnancy loss and pregnancy complications. The aim of this study is to investigate whether adding hysteroscopy to suction curettage reduces the rates of RPOC and IUA.

NCT ID: NCT04381728 Completed - Clinical trials for Intrauterine Adhesion

PREvention of Intrauterine Adhesion After Hysteroscopic Surgery With Novel deGradable Film

PREG1
Start date: November 18, 2019
Phase: N/A
Study type: Interventional

Intrauterine adhesions (IUA) are the major long-term complication of intrauterine procedures and are associated with pelvic pain, menstrual disorders, obstetrical complication and infertility. Womed Leaf is a medical device specifically designed for intrauterine use that prevents intra-uterine adhesions. It is a film that acts as a mechanical barrier to keep uterus walls separated during healing. It is then naturally discharged through the cervix and vagina in less than 30 days. The PREG1 clinical investigation is designed to evaluate Womed Leaf safety under clinical conditions, in women scheduled for a hysteroscopic myomectomy as well as its efficacy.

NCT ID: NCT04308811 Completed - Clinical trials for Intrauterine Adhesion

Autologous Platelet-Rich Plasma in the Management of Asherman Syndrome

Start date: August 10, 2019
Phase: Phase 2
Study type: Interventional

The aim of the study is to find out the benefit of the platelet-rich plasma in preventing reformation of intrauterine adhesions after adhesiolysis in cases of Asherman syndrome

NCT ID: NCT04232592 Not yet recruiting - Clinical trials for Intrauterine Adhesion

Clinical Safety Study of Human Embryonic Stem Cell Derived Mesenchymal Cells in the Treatment of Moderate and Severe Intrauterine Adhesions

Start date: January 2020
Phase: Phase 1
Study type: Interventional

To observe the clinical safety of intrauterine injection of human embryonic stem cell derived mesenchymal cells in the treatment of moderate and severe intrauterine adhesion, and to preliminarily explore its clinical effectiveness in promoting endometrial regeneration and repair.

NCT ID: NCT04166500 Completed - Clinical trials for Intrauterine Adhesion

Early Outpatient Hysteroscopy Can Prevent Intrauterine Adhesion After Induced Abortion

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

Background: Intrauterine adhesions are a difficult clinical problem for reproductive infertility. The most common cause is uterine cavity surgery and post-abortion (including abortion and spontaneous abortion). After the abortion, the uterine cavity adhesion, when is the key point, the literature is not much ink, early literature has mentioned that after the abortion, the uterus scraping action is scraped in four days and the uterine adhesion will be smaller than one to four weeks. Much more, it seems that the sooner the uterine adhesion factor is excluded, the more it can reduce uterine adhesion, but the uterine curettage itself is a risk factor for uterine adhesion. This early practice, the current clinical application, is not used, Instead, it is a hysteroscopy. Our past clinical observations, as soon as possible after the abortion, outpatient hysteroscopy, can find the tissue factors that may cause adhesion in the uterine cavity as soon as possible, and immediately remove it with an outpatient hysteroscope. Objective: To verify the early outpatient hysteroscopy and reduce the occurrence of intrauterine adhesion after abortion. Expected benefits to patients: Abortion is likely to cause intrauterine adhesions, which may further cause the incidence of reproductive infertility, should be involved before the formation of permanent injury, reduce the adhesion of the uterine cavity. Outpatient hysteroscopy is a simple and easy-to-use examination procedure that is painless and does not require anesthesia. Although it is invasive but has few complications, it is expected to reduce the occurrence of intrauterine adhesion after abortion.

NCT ID: NCT03724617 Completed - Clinical trials for Intrauterine Adhesion

Clinical Study of Umbilical Cord Mesenchymal Stem Cells Combined With Collagen Scaffold in the Treatment of Thin Endometrium

Start date: October 29, 2018
Phase: N/A
Study type: Interventional

This is a non-blind self-control trial. We mainly compare the changes of endometrial thickness,changes in menstrual flow, and improvement in pregnancy before and after stem cell treatment in patients with thin endometrium.